Ulrich Matzner
Institut für Physiologische Chemie and LIMES
Membrane Biology and Lipid Biochemistry Unit
c/o Kekulé-Institut für Organische Chemie und Biochemie
Rheinische Friedrich-Wilhelms-University
Germany
Name/email consistency: high
- Saposin B-dependent reconstitution of arylsulfatase A activity in vitro and in cell culture models of metachromatic leukodystrophy. Matzner, U., Breiden, B., Schwarzmann, G., Yaghootfam, A., Fluharty, A.L., Hasilik, A., Sandhoff, K., Gieselmann, V. J. Biol. Chem. (2009)
- Enzyme replacement improves ataxic gait and central nervous system histopathology in a mouse model of metachromatic leukodystrophy. Matzner, U., Lüllmann-Rauch, R., Stroobants, S., Andersson, C., Weigelt, C., Eistrup, C., Fogh, J., D'Hooge, R., Gieselmann, V. Mol. Ther. (2009)
- Non-inhibitory antibodies impede lysosomal storage reduction during enzyme replacement therapy of a lysosomal storage disease. Matzner, U., Matthes, F., Weigelt, C., Andersson, C., Eistrup, C., Fogh, J., Gieselmann, V. J. Mol. Med. (2008)
- Induction of tolerance to human arylsulfatase A in a mouse model of metachromatic leukodystrophy. Matzner, U., Matthes, F., Herbst, E., Lüllmann-Rauch, R., Callaerts-Vegh, Z., D'Hooge, R., Weigelt, C., Eistrup, C., Fogh, J., Gieselmann, V. Mol. Med. (2007)
- Gene therapy of metachromatic leukodystrophy. Matzner, U., Gieselmann, V. Expert. Opin. Biol. Ther (2005)
- Enzyme replacement improves nervous system pathology and function in a mouse model for metachromatic leukodystrophy. Matzner, U., Herbst, E., Hedayati, K.K., Lüllmann-Rauch, R., Wessig, C., Schröder, S., Eistrup, C., Möller, C., Fogh, J., Gieselmann, V. Hum. Mol. Genet. (2005)
- Bone marrow stem cell gene therapy of arylsulfatase A-deficient mice, using an arylsulfatase A mutant that is hypersecreted from retrovirally transduced donor-type cells. Matzner, U., Schestag, F., Hartmann, D., Lüllmann-Rauch, R., D'Hooge, R., De Deyn, P.P., Gieselmann, V. Hum. Gene Ther. (2001)
