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Makoto Higuchi

Laboratory for Proteolytic Neuroscience

RIKEN Brain Science Institute

Wako, Saitama 351-0198



Name/email consistency: high



  • Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan. 2005


  1. Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors. Higuchi, M., Tomioka, M., Takano, J., Shirotani, K., Iwata, N., Masumoto, H., Maki, M., Itohara, S., Saido, T.C. J. Biol. Chem. (2005) [Pubmed]
  2. 19F and 1H MRI detection of amyloid beta plaques in vivo. Higuchi, M., Iwata, N., Matsuba, Y., Sato, K., Sasamoto, K., Saido, T.C. Nat. Neurosci. (2005) [Pubmed]
  3. Understanding molecular mechanisms of proteolysis in Alzheimer's disease: progress toward therapeutic interventions. Higuchi, M., Iwata, N., Saido, T.C. Biochim. Biophys. Acta (2005) [Pubmed]
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