Makoto Otsuka
Faculty of Sciences and Engineering
Konan University
8-9-1 Okamoto
Higashi-Nada
Japan. Electronic address:
Name/email consistency: high
- Effects of polymorphic transformation on pharmaceutical properties of direct compressed tablets containing theophylline anhydrate bulk powder under high humidity. Otsuka, Y., Yamamoto, M., Abe, H., Otsuka, M. Colloids. Surf. B. Biointerfaces (2013)
- Chemometric evaluation of physicochemical properties of carbonated-apatitic preparations by Fourier transform infrared spectroscopy. Otsuka, M., Papangkorn, K., Baig, A.A., Higuchi, W.I. J. Biomed. Mater. Res. A (2012)
- Determination of carbamazepine polymorphic contents in double-layered tablets using transmittance- and reflectance-near-infrared spectroscopy involving chemometrics. Otsuka, M., Fukui, Y. Drug. Dev. Ind. Pharm (2010)
- Effect of geometrical structure on drug release rate of a three-dimensionally perforated porous apatite/collagen composite cement. Otsuka, M., Nakagawa, H., Ito, A., Higuchi, W.I. J. Pharm. Sci (2010)
- Improvement of theophylline anhydrate stability at high humidity by surface-physicochemical modification. Otsuka, M., Ishii, M. Colloids. Surf. B. Biointerfaces (2010)
- Quantitative evaluation of mefenamic acid polymorphs by terahertz-chemometrics. Otsuka, M., Nishizawa, J., Shibata, J., Ito, M. J. Pharm. Sci (2010)
- Quantitative determination of hydrate content of theophylline powder by chemometric X-ray powder diffraction analysis. Otsuka, M., Kinoshita, H. AAPS. PharmSciTech (2010)
- Nano- and macro-geometrical structural change of caffeine and theophylline anhydrate tablets during hydration process by using X-ray computed tomography. Otsuka, M., Ibe, K., Tokudome, Y., Ohshima, H. Colloids. Surf. B. Biointerfaces (2009)
- Prediction of tablet properties based on near infrared spectra of raw mixed powders by chemometrics: Scale-up factor of blending and tableting processes. Otsuka, M., Yamane, I. J. Pharm. Sci (2009)
- Comparative evaluation of bioactivity of crystalline trypsin for drying by Fourier-transformed infrared spectroscopy. Otsuka, M., Fukui, Y., Ozaki, Y. Colloids. Surf. B. Biointerfaces (2009)
- Efficacy of the injectable calcium phosphate ceramics suspensions containing magnesium, zinc and fluoride on the bone mineral deficiency in ovariectomized rats. Otsuka, M., Oshinbe, A., Legeros, R.Z., Tokudome, Y., Ito, A., Otsuka, K., Higuchi, W.I. J. Pharm. Sci (2008)
- Chemoinformetrical evaluation of dissolution property of indomethacin tablets by near-infrared spectroscopy. Otsuka, M., Tanabe, H., Osaki, K., Otsuka, K., Ozaki, Y. J. Pharm. Sci (2007)
- International harmonization of generic drugs: in vitro dissolution tests for Japanese and American generic tablets. Otsuka, M., Tomita, H., Otsuka, K., Kamae, I., Jorgenson, J.A. Biomed. Mater. Eng (2006)
- Effect of nanostructure on biodegradation behaviors of self-setting apatite/collagen composite cements containing vitamin K2 in rats. Otsuka, M., Kuninaga, T., Otsuka, K., Higuchi, W.I. J. Biomed. Mater. Res. Part B Appl. Biomater. (2006)
- Prediction of tablet hardness based on near infrared spectra of raw mixed powders by chemometrics. Otsuka, M., Yamane, I. J. Pharm. Sci (2006)
- Comparative evaluation of bioactivity change of crystalline trypsin during compression by chemoinformatics and 2-D Fourier-transform infrared spectroscopy. Otsuka, M., Fukui, Y., Otsuka, K., Ozaki, Y. Analyst (2006)
