Makoto Saegusa
Department of Pathology
Kitasato University School of Medicine
1-15-1 Kitasato
Sagamihara
Japan
Name/email consistency: high
- Transcriptional regulation of pro-apoptotic Par-4 by NF-kappaB/p65 and its function in controlling cell kinetics during early events in endometrial tumourigenesis. Saegusa, M., Hashimura, M., Kuwata, T., Okayasu, I. J. Pathol. (2010)
- Pin1 acts as a modulator of cell proliferation through alteration in NF-κB but not β-catenin/TCF4 signalling in a subset of endometrial carcinoma cells. Saegusa, M., Hashimura, M., Kuwata, T. J. Pathol. (2010)
- Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug. Saegusa, M., Hashimura, M., Kuwata, T., Okayasu, I. Am. J. Pathol. (2009)
- Transcription factor Egr1 acts as an upstream regulator of beta-catenin signalling through up-regulation of TCF4 and p300 expression during trans-differentiation of endometrial carcinoma cells. Saegusa, M., Hashimura, M., Kuwata, T., Hamano, M., Watanabe, J., Kawaguchi, M., Okayasu, I. J. Pathol. (2008)
- Crosstalk between NF-kappaB/p65 and beta-catenin/TCF4/p300 signalling pathways through alterations in GSK-3beta expression during trans-differentiation of endometrial carcinoma cells. Saegusa, M., Hashimura, M., Kuwata, T., Hamano, M., Okayasu, I. J. Pathol. (2007)
- A functional role of Cdx2 in beta-catenin signaling during transdifferentiation in endometrial carcinomas. Saegusa, M., Hashimura, M., Kuwata, T., Hamano, M., Wani, Y., Okayasu, I. Carcinogenesis (2007)
- Induction of p16INK4A mediated by beta-catenin in a TCF4-independent manner: implications for alterations in p16INK4A and pRb expression during trans-differentiation of endometrial carcinoma cells. Saegusa, M., Hashimura, M., Kuwata, T., Hamano, M., Okayasu, I. Int. J. Cancer (2006)
- Upregulation of TCF4 expression as a transcriptional target of beta-catenin/p300 complexes during trans-differentiation of endometrial carcinoma cells. Saegusa, M., Hashimura, M., Kuwata, T., Hamano, M., Okayasu, I. Lab. Invest. (2005)
- Beta-catenin simultaneously induces activation of the p53-p21WAF1 pathway and overexpression of cyclin D1 during squamous differentiation of endometrial carcinoma cells. Saegusa, M., Hashimura, M., Kuwata, T., Hamano, M., Okayasu, I. Am. J. Pathol. (2004)
- Up-regulation and nuclear localization of beta-catenin in endometrial carcinoma in response to progesterone therapy. Saegusa, M., Hamano, M., Kuwata, T., Yoshida, T., Hashimura, M., Akino, F., Watanabe, J., Kuramoto, H., Okayasu, I. Cancer Sci. (2003)
- Age-dependent differences in tumor cell polarity in endometrial carcinomas. Saegusa, M., Machida, D., Okayasu, I. J. Cancer Res. Clin. Oncol. (2002)
- beta- Catenin mutations and aberrant nuclear expression during endometrial tumorigenesis. Saegusa, M., Hashimura, M., Yoshida, T., Okayasu, I. Br. J. Cancer (2001)
- Frequent nuclear beta-catenin accumulation and associated mutations in endometrioid-type endometrial and ovarian carcinomas with squamous differentiation. Saegusa, M., Okayasu, I. J. Pathol. (2001)
- Possible associations among expression of p14(ARF), p16(INK4a), p21(WAF1/CIP1), p27(KIP1), and p53 accumulation and the balance of apoptosis and cell proliferation in ovarian carcinomas. Saegusa, M., Machida B, D., Okayasu, I. Cancer (2001)
