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Nicholas R. Leslie

Division of Cell Signalling and Immunology

Wellcome Trust Biocentre

College of Life Sciences

University of Dundee

United Kingdom

[email]@dundee.ac.uk

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Division of Cell Signalling and Immunology, Wellcome Trust Biocentre, College of Life Sciences, University of Dundee, United Kingdom. 2012
  • Division of Molecular Physiology, College of Life Sciences, University of Dundee, The James Black Centre, UK. 2002 - 2009
  • Division of Signal Transduction Therapy, Department of Biochemistry, University of Dundee, Dundee DD1 5EH, U.K. 2000 - 2009

References

  1. The PTEN and Myotubularin Phosphoinositide 3-Phosphatases: Linking Lipid Signalling to Human Disease. Leslie, N.R., Davies, E.M., Sheffield, D.A., Tibarewal, P., Fedele, C.G., Mitchell, C.A. Subcell. Biochem. (2012) [Pubmed]
  2. P-REX2a driving tumorigenesis by PTEN inhibition. Leslie, N.R. Sci. Signal (2009) [Pubmed]
  3. The significance of PTEN's protein phosphatase activity. Leslie, N.R., Maccario, H., Spinelli, L., Davidson, L. Adv. Enzyme Regul. (2009) [Pubmed]
  4. Understanding PTEN regulation: PIP2, polarity and protein stability. Leslie, N.R., Batty, I.H., Maccario, H., Davidson, L., Downes, C.P. Oncogene (2008) [Pubmed]
  5. PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration. Leslie, N.R., Yang, X., Downes, C.P., Weijer, C.J. Curr. Biol. (2007) [Pubmed]
  6. The redox regulation of PI 3-kinase-dependent signaling. Leslie, N.R. Antioxid. Redox Signal. (2006) [Pubmed]
  7. The regulation of cell migration by PTEN. Leslie, N.R., Yang, X., Downes, C.P., Weijer, C.J. Biochem. Soc. Trans. (2005) [Pubmed]
  8. PTEN function: how normal cells control it and tumour cells lose it. Leslie, N.R., Downes, C.P. Biochem. J. (2004) [Pubmed]
  9. Redox regulation of phosphatase function. Leslie, N.R., Lindsay, Y., Ross, S.H., Downes, C.P. Biochem. Soc. Trans. (2004) [Pubmed]
  10. Redox regulation of PI 3-kinase signalling via inactivation of PTEN. Leslie, N.R., Bennett, D., Lindsay, Y.E., Stewart, H., Gray, A., Downes, C.P. EMBO J. (2003) [Pubmed]
  11. PTEN: The down side of PI 3-kinase signalling. Leslie, N.R., Downes, C.P. Cell. Signal. (2002) [Pubmed]
  12. Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases. Leslie, N.R., McLennan, A.G., Safrany, S.T. BMC Biochem. (2002) [Pubmed]
  13. Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions. Leslie, N.R., Bennett, D., Gray, A., Pass, I., Hoang-Xuan, K., Downes, C.P. Biochem. J. (2001) [Pubmed]
  14. Analysis of the cellular functions of PTEN using catalytic domain and C-terminal mutations: differential effects of C-terminal deletion on signalling pathways downstream of phosphoinositide 3-kinase. Leslie, N.R., Gray, A., Pass, I., Orchiston, E.A., Downes, C.P. Biochem. J. (2000) [Pubmed]
 
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