C.A. O'Brien
Division of Endocrinology & Metabolism
Department of Medicine
Center for Osteoporosis & Metabolic Bone Diseases
and the McClellan VAMC
USA
Name/email consistency: high
- Expression levels of gp130 in bone marrow stromal cells determine the magnitude of osteoclastogenic signals generated by IL-6-type cytokines. O'Brien, C.A., Lin, S.C., Bellido, T., Manolagas, S.C. J. Cell. Biochem. (2000)
- STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130-utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroid hormone. O'Brien, C.A., Gubrij, I., Lin, S.C., Saylors, R.L., Manolagas, S.C. J. Biol. Chem. (1999)