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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Tomohiro Osanai

Department of Cardiology

Hirosaki University Graduate School of Medicine

5 Zaifu-cho

Hirosaki 036-8562



Name/email consistency: high



  • Department of Cardiology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Japan. 2001 - 2012


  1. Coupling factor 6-induced activation of ecto-F1F(o) complex induces insulin resistance, mild glucose intolerance and elevated blood pressure in mice. Osanai, T., Tanaka, M., Magota, K., Tomita, H., Okumura, K. Diabetologia (2012) [Pubmed]
  2. Novel pro-atherogenic molecule coupling factor 6 is elevated in patients with stroke: a possible linkage to homocysteine. Osanai, T., Fujiwara, N., Sasaki, S., Metoki, N., Saitoh, G., Tomita, H., Nishimura, T., Shibutani, S., Yokoyama, H., Konta, Y., Magota, K., Okumura, K. Ann. Med. (2010) [Pubmed]
  3. Coupling factor 6 enhances Src-mediated responsiveness to angiotensin II in resistance arterioles and cells. Osanai, T., Tomita, H., Kushibiki, M., Yamada, M., Tanaka, M., Ashitate, T., Echizen, T., Katoh, C., Magota, K., Okumura, K. Cardiovasc. Res. (2009) [Pubmed]
  4. Coupling factor 6-induced prostacyclin inhibition is enhanced in vascular smooth muscle cells from spontaneously hypertensive rats. Osanai, T., Tomita, H., Yamada, M., Tanaka, M., Ashitate, T., Echizen, T., Katoh, C., Magota, K., Okumura, K. J. Hypertens. (2009) [Pubmed]
  5. Coupling factor 6 as a novel vasoactive and proatherogenic peptide in vascular endothelial cells. Osanai, T., Magota, K., Okumura, K. Naunyn Schmiedebergs Arch. Pharmacol. (2009) [Pubmed]
  6. Intracellular signaling for vasoconstrictor coupling factor 6: novel function of beta-subunit of ATP synthase as receptor. Osanai, T., Magota, K., Tanaka, M., Shimada, M., Murakami, R., Sasaki, S., Tomita, H., Maeda, N., Okumura, K. Hypertension (2005) [Pubmed]
  7. Effect of shear stress on asymmetric dimethylarginine release from vascular endothelial cells. Osanai, T., Saitoh, M., Sasaki, S., Tomita, H., Matsunaga, T., Okumura, K. Hypertension (2003) [Pubmed]
  8. Plasma concentration of coupling factor 6 and cardiovascular events in patients with end-stage renal disease. Osanai, T., Nakamura, M., Sasaki, S., Tomita, H., Saitoh, M., Osawa, H., Yamabe, H., Murakami, S., Magota, K., Okumura, K. Kidney Int. (2003) [Pubmed]
  9. Circulating coupling factor 6 in human hypertension: role of reactive oxygen species. Osanai, T., Sasaki, S., Kamada, T., Fujiwara, N., Nakano, T., Tomita, H., Matsunaga, T., Magota, K., Okumura, K. J. Hypertens. (2003) [Pubmed]
  10. Cross talk between prostacyclin and nitric oxide under shear in smooth muscle cell: role in monocyte adhesion. Osanai, T., Akutsu, N., Fujita, N., Nakano, T., Takahashi, K., Guan, W., Okumura, K. Am. J. Physiol. Heart Circ. Physiol. (2001) [Pubmed]
  11. Mitochondrial coupling factor 6 as a potent endogenous vasoconstrictor. Osanai, T., Tanaka, M., Kamada, T., Nakano, T., Takahashi, K., Okada, S., Sirato, K., Magota, K., Kodama, S., Okumura, K. J. Clin. Invest. (2001) [Pubmed]
  12. Mitochondrial coupling factor 6 is present on the surface of human vascular endothelial cells and is released by shear stress. Osanai, T., Okada, S., Sirato, K., Nakano, T., Saitoh, M., Magota, K., Okumura, K. Circulation (2001) [Pubmed]
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