Ossama El-Kabbani
Department of Medicinal Chemistry
Victorian College of Pharmacy
Monash University
(Parkville Campus)
Australia
Name/email consistency: high
- Selectivity determinants of the aldose and aldehyde reductase inhibitor-binding sites. El-Kabbani, O., Podjarny, A. Cell. Mol. Life Sci. (2007)
- Structure of the tetrameric form of human L-Xylulose reductase: probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis. El-Kabbani, O., Carbone, V., Darmanin, C., Ishikura, S., Hara, A. Proteins (2005)
- Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase. El-Kabbani, O., Ishikura, S., Wagner, A., Schulze-Briese, C., Hara, A. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. (2005)
- Sorbitol dehydrogenase: structure, function and ligand design. El-Kabbani, O., Darmanin, C., Chung, R.P. Curr. Med. Chem. (2004)
- Aldose reductase structures: implications for mechanism and inhibition. El-Kabbani, O., Ruiz, F., Darmanin, C., Chung, R.P. Cell. Mol. Life Sci. (2004)
- Crystal structure of human L-xylulose reductase holoenzyme: probing the role of Asn107 with site-directed mutagenesis. El-Kabbani, O., Ishikura, S., Darmanin, C., Carbone, V., Chung, R.P., Usami, N., Hara, A. Proteins (2004)
- High-resolution structures of human aldose reductase holoenzyme in complex with stereoisomers of the potent inhibitor Fidarestat: stereospecific interaction between the enzyme and a cyclic imide type inhibitor. El-Kabbani, O., Darmanin, C., Oka, M., Schulze-Briese, C., Tomizaki, T., Hazemann, I., Mitschler, A., Podjarny, A. J. Med. Chem. (2004)
- Structure of human aldose reductase holoenzyme in complex with statil: an approach to structure-based inhibitor design of the enzyme. El-Kabbani, O., Ramsland, P., Darmanin, C., Chung, R.P., Podjarny, A. Proteins (2003)
- Crystallization and preliminary X-ray diffraction analysis of monkey dimeric dihydrodiol dehydrogenase. El-Kabbani, O., Chung, R.P., Ramsland, P.A., Asada, Y., Ishikura, S., Usami, N., Hara, A. Acta Crystallogr. D Biol. Crystallogr. (2002)
- Crystallization and preliminary crystallographic analysis of human L-xylulose reductase. El-Kabbani, O., Chung, R.P., Ishikura, S., Usami, N., Nakagawa, J., Hara, A. Acta Crystallogr. D Biol. Crystallogr. (2002)
- Aldose and aldehyde reductases: structure-function studies on the coenzyme and inhibitor-binding sites. El-Kabbani, O., Old, S.E., Ginell, S.L., Carper, D.A. Mol. Vis. (1999)
- Structural features of the aldose reductase and aldehyde reductase inhibitor-binding sites. El-Kabbani, O., Wilson, D.K., Petrash, M., Quiocho, F.A. Mol. Vis. (1998)