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Peter L. E. M. van Lent

Dept of Rheumatology

Radboud University Nijmegen Medical Centre

Nijmegen

Netherlands

[email]@*.umcn.nl

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Dept of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands. 2003 - 2011
  • Department of Rheumatology and Advanced Therapeutics, Geert Grooteplein 26-28, 6500 HB Nijmegen, Netherlands. 2007
  • University Medical Center, Nijmegen, Netherlands. 2004

References

  1. Active involvement of "alarmins" S100A8 and S100A9 in regulation of synovial activation and joint destruction during mouse and human osteoarthritis. van Lent, P., Blom, A., Schelbergen, R., Sloetjes, A., Lafeber, F., Lems, W., Cats, H., Vogl, T., Roth, J., van den Berg, W. Arthritis Rheum. (2011) [Pubmed]
  2. S100A8 causes a shift toward expression of activatory Fcγ receptors on macrophages via toll-like receptor 4 and regulates Fcγ receptor expression in synovium during chronic experimental arthritis. van Lent, P.L., Grevers, L.C., Schelbergen, R., Blom, A., Geurts, J., Sloetjes, A., Vogl, T., Roth, J., van den Berg, W.B. Arthritis Rheum. (2010) [Pubmed]
  3. Selectively induced death of macrophages in the synovial lining of murine knee joints using 10B-liposomes and boron neutron capture synovectomy. van Lent, P.L., Krijger, G.C., Hofkens, W., Nievaart, V.A., Sloetjes, A.W., Moss, R.L., Koning, G.A., van den Berg, W.B. Int. J. Radiat. Biol. (2009) [Pubmed]
  4. Scavenger receptor class A type I/II determines matrix metalloproteinase-mediated cartilage destruction and chondrocyte death in antigen-induced arthritis. van Lent, P.L., Hofkens, W., Blom, A.B., Grevers, L., Sloetjes, A., Takahashi, N., van Tits, L.J., Vogl, T., Roth, J., de Winther, M.P., van den Berg, W.B. Arthritis Rheum. (2009) [Pubmed]
  5. Stimulation of chondrocyte-mediated cartilage destruction by S100A8 in experimental murine arthritis. van Lent, P.L., Grevers, L.C., Blom, A.B., Arntz, O.J., van de Loo, F.A., van der Kraan, P., Abdollahi-Roodsaz, S., Srikrishna, G., Freeze, H., Sloetjes, A., Nacken, W., Vogl, T., Roth, J., van den Berg, W.B. Arthritis Rheum. (2008) [Pubmed]
  6. Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis. van Lent, P.L., Grevers, L., Blom, A.B., Sloetjes, A., Mort, J.S., Vogl, T., Nacken, W., van den Berg, W.B., Roth, J. Ann. Rheum. Dis. (2008) [Pubmed]
  7. Toll-like receptor 4 induced FcgammaR expression potentiates early onset of joint inflammation and cartilage destruction during immune complex arthritis: Toll-like receptor 4 largely regulates FcgammaR expression by interleukin 10. van Lent, P.L., Blom, A.B., Grevers, L., Sloetjes, A., van den Berg, W.B. Ann. Rheum. Dis. (2007) [Pubmed]
  8. Fcgamma receptors directly mediate cartilage, but not bone, destruction in murine antigen-induced arthritis: uncoupling of cartilage damage from bone erosion and joint inflammation. van Lent, P.L., Grevers, L., Lubberts, E., de Vries, T.J., Nabbe, K.C., Verbeek, S., Oppers, B., Sloetjes, A., Blom, A.B., van den Berg, W.B. Arthritis Rheum. (2006) [Pubmed]
  9. Expression and localisation of the new metalloproteinase inhibitor RECK (reversion inducing cysteine-rich protein with Kazal motifs) in inflamed synovial membranes of patients with rheumatoid arthritis. van Lent, P.L., Span, P.N., Sloetjes, A.W., Radstake, T.R., van Lieshout, A.W., Heuvel, J.J., Sweep, C.G., van den Berg, W.B. Ann. Rheum. Dis. (2005) [Pubmed]
  10. NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-gamma-stimulated immune complex arthritis. van Lent, P.L., Nabbe, K.C., Blom, A.B., Sloetjes, A., Holthuysen, A.E., Kolls, J., Van De Loo, F.A., Holland, S.M., Van Den Berg, W.B. Arthritis Res. Ther. (2005) [Pubmed]
  11. Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation. van Lent, P.L., Blom, A.B., van der Kraan, P., Holthuysen, A.E., Vitters, E., van Rooijen, N., Smeets, R.L., Nabbe, K.C., van den Berg, W.B. Arthritis Rheum. (2004) [Pubmed]
  12. The inhibitory receptor FcgammaRII reduces joint inflammation and destruction in experimental immune complex-mediated arthritides not only by inhibition of FcgammaRI/III but also by efficient clearance and endocytosis of immune complexes. van Lent, P., Nabbe, K.C., Boross, P., Blom, A.B., Roth, J., Holthuysen, A., Sloetjes, A., Verbeek, S., van den Berg, W. Am. J. Pathol. (2003) [Pubmed]
 
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