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Peter Kovacic

Department of Chemistry&Biochemistry

San Diego State University

San Diego

CA 92182-1030 USA

USA

[email]@*.sdsu.edu

Name/email consistency: high

 
 
 
 
 
 
 

Affiliation

  • Department of Chemistry&Biochemistry, San Diego State University, San Diego, CA 92182-1030 USA, USA. 2001 - 2012

References

  1. Propoxur: a novel mechanism for insecticidal action and toxicity. Kovacic, P., Somanathan, R. Rev. Environ. Contam. Toxicol (2012) [Pubmed]
  2. Recent developments in the mechanism of anticancer agents based on electron transfer, reactive oxygen species and oxidative stress. Kovacic, P., Somanathan, R. Anticancer. Agents. Med. Chem (2011) [Pubmed]
  3. Integrated approach to nitric oxide in animals and plants (mechanism and bioactivity): cell signaling and radicals. Kovacic, P., Somanathan, R. J. Recept. Signal Transduct. Res. (2011) [Pubmed]
  4. Hydroxyurea (therapeutics and mechanism): metabolism, carbamoyl nitroso, nitroxyl, radicals, cell signaling and clinical applications. Kovacic, P. Med. Hypotheses (2011) [Pubmed]
  5. Hydroxamic acids (therapeutics and mechanism): chemistry, acyl nitroso, nitroxyl, reactive oxygen species, and cell signaling. Kovacic, P., Edwards, C.L. J. Recept. Signal Transduct. Res. (2011) [Pubmed]
  6. Multifaceted approach to resveratrol bioactivity: Focus on antioxidant action, cell signaling and safety. Kovacic, P., Somanathan, R. Oxid. Med. Cell. Longev (2010) [Pubmed]
  7. Clinical physiology and mechanism of dizocilpine (MK-801): electron transfer, radicals, redox metabolites and bioactivity. Kovacic, P., Somanathan, R. Oxid. Med. Cell. Longev (2010) [Pubmed]
  8. Electron transfer as a potential cause of diacetyl toxicity in popcorn lung disease. Kovacic, P., Cooksy, A.L. Rev. Environ. Contam. Toxicol (2010) [Pubmed]
  9. Dermal toxicity and environmental contamination: electron transfer, reactive oxygen species, oxidative stress, cell signaling, and protection by antioxidants. Kovacic, P., Somanathan, R. Rev. Environ. Contam. Toxicol (2010) [Pubmed]
  10. Unifying mechanism for metals in toxicity, carcinogenicity and therapeutic action: integrated approach involving electron transfer, oxidative stress, antioxidants, cell signaling and receptors. Kovacic, P., Somanathan, R. J. Recept. Signal Transduct. Res. (2010) [Pubmed]
  11. Integrated approach to the mechanisms of thyroid toxins: electron transfer, reactive oxygen species, oxidative stress, cell signaling, receptors, and antioxidants. Kovacic, P., Edwards, C. J. Recept. Signal Transduct. Res. (2010) [Pubmed]
  12. Bioelectrochemistry, reactive oxygen species, receptors, and cell signaling: how interrelated?. Kovacic, P., Hall, M.E. J. Recept. Signal Transduct. Res. (2010) [Pubmed]
  13. Novel, unifying mechanism for mescaline in the central nervous system: electrochemistry, catechol redox metabolite, receptor, cell signaling and structure activity relationships. Kovacic, P., Somanathan, R. Oxid. Med. Cell. Longev (2009) [Pubmed]
  14. Pulmonary toxicity and environmental contamination: radicals, electron transfer, and protection by antioxidants. Kovacic, P., Somanathan, R. Rev. Environ. Contam. Toxicol (2009) [Pubmed]
  15. Zolpidem, a clinical hypnotic that affects electronic transfer, alters synaptic activity through potential GABA receptors in the nervous system without significant free radical generation. Kovacic, P., Somanathan, R. Oxid. Med. Cell. Longev (2009) [Pubmed]
  16. Unifying electrostatic mechanism for metal cations in receptors and cell signaling. Kovacic, P. J. Recept. Signal Transduct. Res. (2008) [Pubmed]
  17. Does structural commonality of metal complex formation by PAC-1 (anticancer), DHBNH (anti-HIV), AHL (autoinducer), and UCS1025A (anticancer) denote mechanistic similarity? Signal transduction and medical aspects. Kovacic, P. J. Recept. Signal Transduct. Res. (2008) [Pubmed]
  18. Ototoxicity and noise trauma: electron transfer, reactive oxygen species, cell signaling, electrical effects, and protection by antioxidants: practical medical aspects. Kovacic, P., Somanathan, R. Med. Hypotheses (2008) [Pubmed]
  19. Integrated approach to immunotoxicity: electron transfer, reactive oxygen species, antioxidants, cell signaling, and receptors. Kovacic, P., Somanathan, R. J. Recept. Signal Transduct. Res. (2008) [Pubmed]
  20. Unifying mechanism for anticancer agents involving electron transfer and oxidative stress: clinical implications. Kovacic, P. Med. Hypotheses (2007) [Pubmed]
  21. Unifying mechanism for bacterial cell signalers (4,5-dihydroxy-2,3-pentanedione, lactones and oligopeptides): electron transfer and reactive oxygen species. Practical medical features. Kovacic, P. Med. Hypotheses (2007) [Pubmed]
  22. Protein electron transfer (mechanism and reproductive toxicity): iminium, hydrogen bonding, homoconjugation, amino acid side chains (redox and charged), and cell signaling. Kovacic, P. Birth Defects Res. C Embryo Today (2007) [Pubmed]
  23. Unifying electrostatic mechanism for phosphates and sulfates in cell signaling. Kovacic, P., Draskovich, C.D., Pozos, R.S. J. Recept. Signal Transduct. Res. (2007) [Pubmed]
  24. Unifying electrostatic mechanism for receptor-ligand activity. Kovacic, P., Pozos, R.S., Draskovich, C.D. J. Recept. Signal Transduct. Res. (2007) [Pubmed]
  25. Bioelectronome. Integrated approach to receptor chemistry, radicals, electrochemistry, cell signaling, and physiological effects based on electron transfer. Kovacic, P., Pozos, R.S. J. Recept. Signal Transduct. Res. (2007) [Pubmed]
  26. Cell signaling (mechanism and reproductive toxicity): redox chains, radicals, electrons, relays, conduit, electrochemistry, and other medical implications. Kovacic, P., Pozos, R.S. Birth Defects Res. C Embryo Today (2006) [Pubmed]
  27. Mechanism of teratogenesis: electron transfer, reactive oxygen species, and antioxidants. Kovacic, P., Somanathan, R. Birth Defects Res. C Embryo Today (2006) [Pubmed]
  28. Novel electrochemical approach to enhanced toxicity of 4-oxo-2-nonenal vs. 4-hydroxy-2-nonenal (role of imine): oxidative stress and therapeutic modalities. Kovacic, P. Med. Hypotheses (2006) [Pubmed]
  29. Iminium metabolite mechanism for nicotine toxicity and addiction: Oxidative stress and electron transfer. Kovacic, P., Cooksy, A. Med. Hypotheses (2005) [Pubmed]
  30. Role of oxidative metabolites of cocaine in toxicity and addiction: oxidative stress and electron transfer. Kovacic, P. Med. Hypotheses (2005) [Pubmed]
  31. Unifying mechanism for toxicity and addiction by abused drugs: electron transfer and reactive oxygen species. Kovacic, P., Cooksy, A.L. Med. Hypotheses (2005) [Pubmed]
  32. Role of diacetyl metabolite in alcohol toxicity and addiction via electron transfer and oxidative stress. Kovacic, P., Cooksy, A.L. Arch. Toxicol. (2005) [Pubmed]
  33. Cardiovascular toxicity from the perspective of oxidative stress, electron transfer, and prevention by antioxidants. Kovacic, P., Thurn, L.A. Curr. Vasc. Pharmacol (2005) [Pubmed]
  34. Unifying mechanism for addiction and toxicity of abused drugs with application to dopamine and glutamate mediators: electron transfer and reactive oxygen species. Kovacic, P. Med. Hypotheses (2005) [Pubmed]
  35. Fundamental, electron transfer mechanism by pyrylium-type ions for the anticancer drugs 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid (FAA). Kovacic, P. Curr. Med. Chem. Anticancer. Agents (2005) [Pubmed]
  36. Mechanism of mitochondrial uncouplers, inhibitors, and toxins: focus on electron transfer, free radicals, and structure-activity relationships. Kovacic, P., Pozos, R.S., Somanathan, R., Shangari, N., O'Brien, P.J. Curr. Med. Chem. (2005) [Pubmed]
  37. Systemic lupus erythematosus and other autoimmune diseases from endogenous and exogenous agents: unifying theme of oxidative stress. Kovacic, P., Jacintho, J.D. Mini. Rev. Med. Chem (2003) [Pubmed]
  38. Mechanism of organophosphates (nerve gases and pesticides) and antidotes: electron transfer and oxidative stress. Kovacic, P. Curr. Med. Chem. (2003) [Pubmed]
  39. Mechanism of drug and toxic actions of gossypol: focus on reactive oxygen species and electron transfer. Kovacic, P. Curr. Med. Chem. (2003) [Pubmed]
  40. Nephrotoxins: widespread role of oxidative stress and electron transfer. Kovacic, P., Sacman, A., Wu-Weis, M. Curr. Med. Chem. (2002) [Pubmed]
  41. Reproductive toxins: pervasive theme of oxidative stress and electron transfer. Kovacic, P., Jacintho, J.D. Curr. Med. Chem. (2001) [Pubmed]
 
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