Jens Plaschke
Department of Surgical Research
Carl Gustav Carus Klinikum
Technical University Dresden
Germany
Name/email consistency: high
- Compound heterozygosity for two MSH6 mutations in a patient with early onset of HNPCC-associated cancers, but without hematological malignancy and brain tumor. Plaschke, J., Linnebacher, M., Kloor, M., Gebert, J., Cremer, F.W., Tinschert, S., Aust, D.E., von Knebel Doeberitz, M., Schackert, H.K. Eur. J. Hum. Genet. (2006)
- Loss of MSH3 protein expression is frequent in MLH1-deficient colorectal cancer and is associated with disease progression. Plaschke, J., Krüger, S., Jeske, B., Theissig, F., Kreuz, F.R., Pistorius, S., Saeger, H.D., Iaccarino, I., Marra, G., Schackert, H.K. Cancer Res. (2004)
- Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue. Plaschke, J., Krüger, S., Dietmaier, W., Gebert, J., Sutter, C., Mangold, E., Pagenstecher, C., Holinski-Feder, E., Schulmann, K., Möslein, G., Rüschoff, J., Engel, C., Evans, G., Schackert, H.K. Hum. Mutat. (2004)
- Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium. Plaschke, J., Engel, C., Krüger, S., Holinski-Feder, E., Pagenstecher, C., Mangold, E., Moeslein, G., Schulmann, K., Gebert, J., von Knebel Doeberitz, M., Rüschoff, J., Loeffler, M., Schackert, H.K. J. Clin. Oncol. (2004)
- Methylenetetrahydrofolate reductase polymorphisms and risk of sporadic and hereditary colorectal cancer with or without microsatellite instability. Plaschke, J., Schwanebeck, U., Pistorius, S., Saeger, H.D., Schackert, H.K. Cancer Lett. (2003)
- Genomic rearrangements of hMSH6 contribute to the genetic predisposition in suspected hereditary non-polyposis colorectal cancer syndrome. Plaschke, J., Rüschoff, J., Schackert, H.K. J. Med. Genet. (2003)
- Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation. Plaschke, J., Krüger, S., Pistorius, S., Theissig, F., Saeger, H.D., Schackert, H.K. Int. J. Cancer (2002)
- Sequence analysis of the mismatch repair gene hMSH6 in the germline of patients with familial and sporadic colorectal cancer. Plaschke, J., Kruppa, C., Tischler, R., Bocker, T., Pistorius, S., Dralle, H., Rüschoff, J., Saeger, H.D., Fishel, R., Schackert, H.K. Int. J. Cancer (2000)
- Quantitative differences between aberrant transcripts which occur as common isoforms and due to mutation-based exon skipping of the mismatch repair gene hMLH1. Plaschke, J., Bulitta, C., Saeger, H.D., Schackert, H.K. Clin. Chem. Lab. Med. (1999)
