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Qun Li

Cancer Research

Abbott Laboratories

60064-6101

Abbott Park

USA

[email]@abbott.com

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Cancer Research, Abbott Laboratories, 60064-6101, Abbott Park, USA. 2002 - 2006
  • Abbott Laboratories, Cancer Research, Global Pharmaceutical Discovery, R47S, AP10, 100 Abbott Park Rd, USA. 2002
  • Pharmaceutical Products Division, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, USA. 2000

References

  1. Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation. Li, Q., Li, T., Zhu, G.D., Gong, J., Claibone, A., Dalton, C., Luo, Y., Johnson, E.F., Shi, Y., Liu, X., Klinghofer, V., Bauch, J.L., Marsh, K.C., Bouska, J.J., Arries, S., De Jong, R., Oltersdorf, T., Stoll, V.S., Jakob, C.G., Rosenberg, S.H., Giranda, V.L. Bioorg. Med. Chem. Lett. (2006) [Pubmed]
  2. Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer. Li, Q., Woods, K.W., Thomas, S., Zhu, G.D., Packard, G., Fisher, J., Li, T., Gong, J., Dinges, J., Song, X., Abrams, J., Luo, Y., Johnson, E.F., Shi, Y., Liu, X., Klinghofer, V., Des Jong, R., Oltersdorf, T., Stoll, V.S., Jakob, C.G., Rosenberg, S.H., Giranda, V.L. Bioorg. Med. Chem. Lett. (2006) [Pubmed]
  3. Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors. Li, Q., Woods, K.W., Wang, W., Lin, N.H., Claiborne, A., Gu, W.Z., Cohen, J., Stoll, V.S., Hutchins, C., Frost, D., Rosenberg, S.H., Sham, H.L. Bioorg. Med. Chem. Lett. (2005) [Pubmed]
  4. Benzimidazolones and indoles as non-thiol farnesyltransferase inhibitors based on tipifarnib scaffold: synthesis and activity. Li, Q., Li, T., Woods, K.W., Gu, W.Z., Cohen, J., Stoll, V.S., Galicia, T., Hutchins, C., Frost, D., Rosenberg, S.H., Sham, H.L. Bioorg. Med. Chem. Lett. (2005) [Pubmed]
  5. Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors. Li, Q., Claiborne, A., Li, T., Hasvold, L., Stoll, V.S., Muchmore, S., Jakob, C.G., Gu, W., Cohen, J., Hutchins, C., Frost, D., Rosenberg, S.H., Sham, H.L. Bioorg. Med. Chem. Lett. (2004) [Pubmed]
  6. Synthesis and activity of 1-aryl-1'-imidazolyl methyl ethers as non-thiol farnesyltransferase inhibitors. Li, Q., Wang, G.T., Li, T., Gwaltney, S.L., Woods, K.W., Claiborne, A., Wang, X., Gu, W., Cohen, J., Stoll, V.S., Hutchins, C., Frost, D., Rosenberg, S.H., Sham, H.L. Bioorg. Med. Chem. Lett. (2004) [Pubmed]
  7. Synthesis and biological evaluation of 2-indolyloxazolines as a new class of tubulin polymerization inhibitors. Discovery of A-289099 as an orally active antitumor agent. Li, Q., Woods, K.W., Claiborne, A., Gwaltney, S.L., Barr, K.J., Liu, G., Gehrke, L., Credo, R.B., Hui, Y.H., Lee, J., Warner, R.B., Kovar, P., Nukkala, M.A., Zielinski, N.A., Tahir, S.K., Fitzgerald, M., Kim, K.H., Marsh, K., Frost, D., Ng, S.C., Rosenberg, S., Sham, H.L. Bioorg. Med. Chem. Lett. (2002) [Pubmed]
  8. Targeting serine/threonine protein kinase B/Akt and cell-cycle checkpoint kinases for treating cancer. Li, Q., Zhu, G.D. Curr. Top. Med. Chem (2002) [Pubmed]
  9. The 2-pyridone antibacterial agents: bacterial topoisomerase inhibitors. Li, Q., Mitscher, L.A., Shen, L.L. Med. Res. Rev (2000) [Pubmed]
 
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