Roger M. Phillips
Clinical Oncology Unit and School of Pharmacy
University of Bradford
Bradford BD7 1DP
U.K
Name/email consistency: high
- Detection of (NAD(P)H:Quinone oxidoreductase-1, EC 1.6.99.2) 609C-->T and 465C-->T polymorphisms in formalin-fixed, paraffin-embedded human tumour tissue using PCR-RFLP. Phillips, R.M., Basu, S., Brown, J.E., Flannigan, G.M., Loadman, P.M., Martin, S.W., Naylor, B., Puri, R., Shah, T. Int. J. Oncol. (2004)
- Pharmacological and biological evaluation of a series of substituted 1,4-naphthoquinone bioreductive drugs. Phillips, R.M., Jaffar, M., Maitland, D.J., Loadman, P.M., Shnyder, S.D., Steans, G., Cooper, P.A., Race, A., Patterson, A.V., Stratford, I.J. Biochem. Pharmacol. (2004)
- Influence of extracellular pH on the cytotoxicity and DNA damage of a series of indolequinone compounds. Phillips, R.M., Ward, T.H. Anticancer Res. (2001)
- Genotyping of NAD(P)H:quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mitomycin C chemotherapy in vivo(1). Phillips, R.M., Burger, A.M., Fiebig, H.H., Double, J.A. Biochem. Pharmacol. (2001)
- Predicting tumor responses to mitomycin C on the basis of DT-diaphorase activity or drug metabolism by tumor homogenates: implications for enzyme-directed bioreductive drug development. Phillips, R.M., Burger, A.M., Loadman, P.M., Jarrett, C.M., Swaine, D.J., Fiebig, H.H. Cancer Res. (2000)
- AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics. Phillips, R.M. Expert. Opin. Investig. Drugs (2000)
- Inhibition of DT-diaphorase (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid (FAA): implications for bioreductive drug development. Phillips, R.M. Biochem. Pharmacol. (1999)
- Bioreductive activation of a series of indolequinones by human DT-diaphorase: structure-activity relationships. Phillips, R.M., Naylor, M.A., Jaffar, M., Doughty, S.W., Everett, S.A., Breen, A.G., Choudry, G.A., Stratford, I.J. J. Med. Chem. (1999)