Roger L. Papke
Department of Pharmacology and Therapeutics
University of Florida
P.O. Box 100267
Gainesville
Name/email consistency: high
- Intrinsically Low Open Probability of α7 Nicotinic Acetylcholine Receptors Can Be Overcome by Positive Allosteric Modulation and Serum Factors Leading to the Generation of Excitotoxic Currents at Physiological Temperatures. Williams, D.K., Peng, C., Kimbrell, M.R., Papke, R.L. Mol. Pharmacol. (2012)
- Investigation of the Molecular Mechanism of the α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator PNU-120596 Provides Evidence for Two Distinct Desensitized States. Williams, D.K., Wang, J., Papke, R.L. Mol. Pharmacol. (2011)
- Electrophysiological perspectives on the therapeutic use of nicotinic acetylcholine receptor partial agonists. Papke, R.L., Trocmé-Thibierge, C., Guendisch, D., Al Rubaiy, S.A., Bloom, S.A. J. Pharmacol. Exp. Ther. (2011)
- Cysteine accessibility analysis of the human alpha7 nicotinic acetylcholine receptor ligand-binding domain identifies L119 as a gatekeeper. Papke, R.L., Stokes, C., Williams, D.K., Wang, J., Horenstein, N.A. Neuropharmacology (2011)
- Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. Papke, R.L., Wecker, L., Stitzel, J.A. J. Pharmacol. Exp. Ther. (2010)
- alpha4beta2 Nicotinic acetylcholine receptors, willing if able. Papke, R.L. Br. J. Pharmacol. (2010)
- Tricks of perspective: insights and limitations to the study of macroscopic currents for the analysis of nAChR activation and desensitization. Papke, R.L. J. Mol. Neurosci. (2010)
- Activation and desensitization of nicotinic alpha7-type acetylcholine receptors by benzylidene anabaseines and nicotine. Papke, R.L., Kem, W.R., Soti, F., López-Hernández, G.Y., Horenstein, N.A. J. Pharmacol. Exp. Ther. (2009)
- High throughput electrophysiology with Xenopus oocytes. Papke, R.L., Smith-Maxwell, C. Comb. Chem. High Throughput Screen. (2009)
- Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras. Papke, R.L., Dwoskin, L.P., Crooks, P.A., Zheng, G., Zhang, Z., McIntosh, J.M., Stokes, C. Neuropharmacology (2008)
- The pharmacological activity of nicotine and nornicotine on nAChRs subtypes: relevance to nicotine dependence and drug discovery. Papke, R.L., Dwoskin, L.P., Crooks, P.A. J. Neurochem. (2007)
- Estimation of both the potency and efficacy of alpha7 nAChR agonists from single-concentration responses. Papke, R.L. Life Sci. (2006)
- The effects of subunit composition on the inhibition of nicotinic receptors by the amphipathic blocker 2,2,6,6-tetramethylpiperidin-4-yl heptanoate. Papke, R.L., Buhr, J.D., Francis, M.M., Choi, K.I., Thinschmidt, J.S., Horenstein, N.A. Mol. Pharmacol. (2005)
- Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist. Papke, R.L., Schiff, H.C., Jack, B.A., Horenstein, N.A. Neurosci. Lett. (2005)
- The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion. Papke, R.L., Zheng, G., Horenstein, N.A., Dwoskin, L.P., Crooks, P.A. Bioorg. Med. Chem. Lett. (2005)
- Rhesus monkey alpha7 nicotinic acetylcholine receptors: comparisons to human alpha7 receptors expressed in Xenopus oocytes. Papke, R.L., McCormack, T.J., Jack, B.A., Wang, D., Bugaj-Gaweda, B., Schiff, H.C., Buhr, J.D., Waber, A.J., Stokes, C. Eur. J. Pharmacol. (2005)
- Effects at a distance in alpha 7 nAChR selective agonists: benzylidene substitutions that regulate potency and efficacy. Papke, R.L., Meyer, E.M., Lavieri, S., Bollampally, S.R., Papke, T.A., Horenstein, N.A., Itoh, Y., Porter Papke, J.K. Neuropharmacology (2004)
