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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 72 documents. Results 1 - 10.

Caenorhabditis elegans
Gene: ... High impact information on akt- 2 This demonstrates that Akt/ PKB activity is not necessarily dependent on AGE- 1 PI3K activity. akt- 1 and akt- 2 are expressed in overlapping patterns in the nervous..., akt- 1 and akt- 2 regulate development in response to environmental cues by controlling the FOXO...
Rattus norvegicus
Gene: ... Disease relevance of Akt2 Insulin- stimulated insulin receptor substrate 2 and Akt- 2 phosphorylation were significantly blunted in IUGR rats. High impact information on Akt2 In addition to increasing phosphorylation, contraction in situ significantly increased the activity of all three Akt isoforms( Akt1> Akt2... / Synonyms: Protein kinase Akt-2
Homo sapiens
Gene: ... Disease relevance of AKT2 In addition, downstream effectors of PI3- kinase, AKT1 and AKT2, have... of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric..., AKT2 protein predominantly localized adjacent to the collagen IV matrix during cellular attachment... / Synonyms: Protein kinase Akt-2
Mus musculus
Gene: ... Disease relevance of Akt2 Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Loss of Akt2 also impaired... to collagen and ADP. In addition, Akt2/ PKBbeta- deficient mice exhibit fed and fasting hyperglycemia... / Synonyms: Protein kinase Akt-2
Gallus gallus
Gene: ... High impact information on AKT2 Cloning of the chicken akt2 homologue revealed a high degree of amino acid homology to its mammalian counterparts within the catalytic domain, plus complete conservation of the putative Thr( 308) and Ser( 474) phosphorylation sites....
Arabidopsis thaliana
Gene: ... that the loss of AKT2/ 3 indeed affects the Ca2+ dependence of guard cell inward rectifier. All of the data...Disease relevance of AKT2 We report here that the inward- rectifying potassium channels KAT1 and AKT2 were functionally expressed in K+ uptake- deficient Escherichia coli. High impact information... / Synonyms: AKT2; AKT2/3
Xenopus (Silurana) tropicalis
Gene: Synonyms: v-akt2
MeSH term: ... of Moloney murine leukemia virus- induced T cell lymphomas in rats. AKT2, a putative oncogene encoding... feline and avian retroviral transforming genes, all of which encode functionally related proteins...
MeSH term: ... , AKT1 and AKT2, have been found to be amplified or activated in human tumours, including ovarian cancer... predisposition -- often associated with the BRCA1 and BRCA2 genes -- in at least 5% to 10% of all epithelial... tumor growth in vivo. Concentration- dependent antiproliferative effects of PD- 0332991 were seen in all...

 

 
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