Chemical Compound Review:
QCR-51 4-[4-[[2-(4-chlorophenyl) phenyl]methyl]pip...
Synonyms:
PubChem20162, ABT-737, S1002_Selleck, ABT737, CHEMBL376408, ...
- The Bcl-2/Bcl-XL family inhibitor ABT-737 sensitizes ovarian cancer cells to carboplatin. Witham, J., Valenti, M.R., De-Haven-Brandon, A.K., Vidot, S., Eccles, S.A., Kaye, S.B., Richardson, A. Clin. Cancer Res. (2007)
- Induction of Noxa sensitizes human colorectal cancer cells expressing Mcl-1 to the small-molecule Bcl-2/Bcl-xL inhibitor, ABT-737. Okumura, K., Huang, S., Sinicrope, F.A. Clin. Cancer Res. (2008)
- ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells. Kline, M.P., Rajkumar, S.V., Timm, M.M., Kimlinger, T.K., Haug, J.L., Lust, J.A., Greipp, P.R., Kumar, S. Leukemia (2007)
- A novel Bcl-2/Bcl-X(L)/Bcl-w inhibitor ABT-737 as therapy in multiple myeloma. Chauhan, D., Velankar, M., Brahmandam, M., Hideshima, T., Podar, K., Richardson, P., Schlossman, R., Ghobrial, I., Raje, N., Munshi, N., Anderson, K.C. Oncogene (2007)
- ABT-737 Induces Apoptosis in Mantle Cell Lymphoma Cells with a Bcl-2high/Mcl-1low Profile and Synergizes with Other Antineoplastic Agents. Touzeau, C., Dousset, C., Bodet, L., Gomez-Bougie, P., Bonnaud, S., Moreau, A., Moreau, P., Pellat-Deceunynk, C., Amiot, M., Le Gouill, S. Clin. Cancer Res. (2011)
- Tipping the Noxa/Mcl-1 Balance Overcomes ABT-737 Resistance in Chronic Lymphocytic Leukemia. Tromp, J.M., Geest, C.R., Breij, E.C., Elias, J.A., van Laar, J., Luijks, D.M., Kater, A.P., Beaumont, T., van Oers, M.H., Eldering, E. Clin. Cancer Res. (2012)
- ABT-737 induces expression of the death receptor 5 and sensitizes human cancer cells to TRAIL-induced apoptosis. Song, J.H., Kandasamy, K., Kraft, A.S. J. Biol. Chem. (2008)