Chemical Compound Review:
Etropain 5-chloro-2-(6-methylpyridin- 3-yl)-3-(4...
Synonyms:
Torcoxia, Arcoxia, Kingcox, Nucoxia, Etoricoxib, ...
Niederberger,
Manderscheid,
Geisslinger,
Tsoukas,
Eyster,
Shingo,
Mukhopadhyay,
Giallella,
Curtis,
Reicin,
Melian,
van der Heijde,
Baraf,
Ramos-Remus,
Calin,
Weaver,
Schiff,
James,
Markind,
Reicin,
Melian,
Dougados,
El Miedany,
Youssef,
Ahmed,
El Gaafary,
Chan,
Rodrigues,
Halpin,
Geer,
Cui,
Woolf,
Matthews,
Gottesdiener,
Larson,
Lasseter,
Agrawal,
Riendeau,
Percival,
Brideau,
Charleson,
Dubé,
Ethier,
Falgueyret,
Friesen,
Gordon,
Greig,
Guay,
Mancini,
Ouellet,
Wong,
Xu,
Boyce,
Visco,
Girard,
Prasit,
Zamboni,
Rodger,
Gresser,
Ford-Hutchinson,
Young,
Chan,
Watson,
Bolognese,
Yu,
Krupa,
Curtis,
Dalton,
Clas,
Singh,
Khougaz,
Bilbeisi,
Curtis,
Ng,
Yu,
Shingo,
Bergman,
McCormick,
Reicin,
Hunt,
Harper,
Callegari,
Yu,
Quan,
Evans,
James,
Bowen,
Rashid,
Kassahun,
McIntosh,
Shou,
Walsh,
Rodeheffer,
Slaughter,
Geer,
Halpin,
Agrawal,
Rodrigues,
- Etoricoxib. Cochrane, D.J., Jarvis, B., Keating, G.M. Drugs (2002)
- Results of a randomized, dose-ranging trial of etoricoxib in patients with osteoarthritis. Gottesdiener, K., Schnitzer, T., Fisher, C., Bockow, B., Markenson, J., Ko, A., DeTora, L., Curtis, S., Geissler, L., Gertz, B.J. Rheumatology (Oxford, England) (2002)
- Complementary studies of the gastrointestinal safety of the cyclo-oxygenase-2-selective inhibitor etoricoxib. Hunt, R.H., Harper, S., Callegari, P., Yu, C., Quan, H., Evans, J., James, C., Bowen, B., Rashid, F. Aliment. Pharmacol. Ther. (2003)
- The gastrointestinal safety of the COX-2 selective inhibitor etoricoxib assessed by both endoscopy and analysis of upper gastrointestinal events. Hunt, R.H., Harper, S., Watson, D.J., Yu, C., Quan, H., Lee, M., Evans, J.K., Oxenius, B. Am. J. Gastroenterol. (2003)
- The gastrointestinal safety and effect on disease activity of etoricoxib, a selective cox-2 inhibitor in inflammatory bowel diseases. El Miedany, Y., Youssef, S., Ahmed, I., El Gaafary, M. Am. J. Gastroenterol. (2006)
- Evaluation of the efficacy and safety of etoricoxib in the treatment of hemophilic arthropathy. Tsoukas, C., Eyster, M.E., Shingo, S., Mukhopadhyay, S., Giallella, K.M., Curtis, S.P., Reicin, A.S., Melian, A. Blood (2006)
- Evaluation of the efficacy of etoricoxib in ankylosing spondylitis: results of a fifty-two-week, randomized, controlled study. van der Heijde, D., Baraf, H.S., Ramos-Remus, C., Calin, A., Weaver, A.L., Schiff, M., James, M., Markind, J.E., Reicin, A.S., Melian, A., Dougados, M. Arthritis Rheum. (2005)
- Clinical pharmacology of novel selective COX-2 inhibitors. Tacconelli, S., Capone, M.L., Patrignani, P. Curr. Pharm. Des. (2004)
- Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: comparison to sulfonamide COX-2 inhibitors and NSAIDs. Walter, M.F., Jacob, R.F., Day, C.A., Dahlborg, R., Weng, Y., Mason, R.P. Atherosclerosis (2004)
- Evaluation of the comparative efficacy of etoricoxib and ibuprofen for treatment of patients with osteoarthritis: A randomized, double-blind, placebo-controlled trial. Wiesenhutter, C.W., Boice, J.A., Ko, A., Sheldon, E.A., Murphy, F.T., Wittmer, B.A., Aversano, M.L., Reicin, A.S. Mayo Clin. Proc. (2005)
- Renal effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs in controlled clinical trials. Curtis, S.P., Ng, J., Yu, Q., Shingo, S., Bergman, G., McCormick, C.L., Reicin, A.S. Clinical therapeutics. (2004)
- The analgesic efficacy of etoricoxib compared with oxycodone/acetaminophen in an acute postoperative pain model: a randomized, double-blind clinical trial. Chang, D.J., Desjardins, P.J., King, T.R., Erb, T., Geba, G.P. Anesth. Analg. (2004)
- A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritis. Zacher, J., Feldman, D., Gerli, R., Scott, D., Hou, S.M., Uebelhart, D., Rodger, I.W., Ozturk, Z.E. Current medical research and opinion. (2003)
- Analysis of interaction between etoricoxib and tramadol against mechanical hyperalgesia of spinal cord injury in rats. Singh, V.P., Patil, C.S., Kulkarni, S.K. Life Sci. (2006)
- Pharmacokinetics of etoricoxib in patients with renal impairment. Agrawal, N.G., Matthews, C.Z., Mazenko, R.S., Kline, W.F., Woolf, E.J., Porras, A.G., Geer, L.A., Wong, P.H., Cho, M., Cote, J., Marbury, T.C., Moncrief, J.W., Alcorn, H., Swan, S., Sack, M.R., Robson, R.A., Petty, K.J., Schwartz, J.I., Gottesdiener, K.M. Journal of clinical pharmacology. (2004)
- Single- and multiple-dose pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, in man. Agrawal, N.G., Porras, A.G., Matthews, C.Z., Rose, M.J., Woolf, E.J., Musser, B.J., Dynder, A.L., Mazina, K.E., Lasseter, K.C., Hunt, T.L., Schwartz, J.I., McCrea, J.B., Gottesdiener, K.M. Journal of clinical pharmacology. (2003)
- Characterization of etoricoxib, a novel, selective COX-2 inhibitor. Dallob, A., Hawkey, C.J., Greenberg, H., Wight, N., De Schepper, P., Waldman, S., Wong, P., DeTora, L., Gertz, B., Agrawal, N., Wagner, J., Gottesdiener, K. Journal of clinical pharmacology. (2003)
- Safety of etoricoxib, a specific cyclooxygenase-2 inhibitor, in asthmatic patients with aspirin-exacerbated respiratory disease. El Miedany, Y., Youssef, S., Ahmed, I., El Gaafary, M. Ann. Allergy Asthma Immunol. (2006)
- Role of human liver cytochrome P4503A in the metabolism of etoricoxib, a novel cyclooxygenase-2 selective inhibitor. Kassahun, K., McIntosh, I.S., Shou, M., Walsh, D.J., Rodeheffer, C., Slaughter, D.E., Geer, L.A., Halpin, R.A., Agrawal, N., Rodrigues, A.D. Drug Metab. Dispos. (2001)
- Absorption, metabolism, and excretion of etoricoxib, a potent and selective cyclooxygenase-2 inhibitor, in healthy male volunteers. Rodrigues, A.D., Halpin, R.A., Geer, L.A., Cui, D., Woolf, E.J., Matthews, C.Z., Gottesdiener, K.M., Larson, P.J., Lasseter, K.C., Agrawal, N.G. Drug Metab. Dispos. (2003)
- Protective effects of etoricoxib, a selective inhibitor of cyclooxygenase-2, in experimental periodontitis in rats. Holzhausen, M., Spolidorio, D.M., Muscará, M.N., Hebling, J., Spolidorio, L.C. J. Periodont. Res. (2005)
- Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2. Riendeau, D., Percival, M.D., Brideau, C., Charleson, S., Dubé, D., Ethier, D., Falgueyret, J.P., Friesen, R.W., Gordon, R., Greig, G., Guay, J., Mancini, J., Ouellet, M., Wong, E., Xu, L., Boyce, S., Visco, D., Girard, Y., Prasit, P., Zamboni, R., Rodger, I.W., Gresser, M., Ford-Hutchinson, A.W., Young, R.N., Chan, C.C. J. Pharmacol. Exp. Ther. (2001)
- A mechanistic perspective on the specificity and extent of COX-2 inhibition in pregnancy. Chan, V.S. Drug safety : an international journal of medical toxicology and drug experience. (2004)
- Different COX-independent effects of the COX-2 inhibitors etoricoxib and lumiracoxib. Niederberger, E., Manderscheid, C., Geisslinger, G. Biochem. Biophys. Res. Commun. (2006)
- Use of gastroprotective agents and discontinuations due to dyspepsia with the selective cyclooxygenase-2 inhibitor etoricoxib compared with non-selective NSAIDs. Watson, D.J., Bolognese, J.A., Yu, C., Krupa, D., Curtis, S. Current medical research and opinion. (2004)
- Etoricoxib in acute pain associated with dental surgery: a randomized, double-blind, placebo- and active comparator-controlled dose-ranging study. Malmstrom, K., Sapre, A., Couglin, H., Agrawal, N.G., Mazenko, R.S., Fricke, J.R. Clinical therapeutics. (2004)
- Investigating the hydrate conversion propensity of different etoricoxib lots. Dalton, C.R., Clas, S.D., Singh, J., Khougaz, K., Bilbeisi, R. Journal of pharmaceutical sciences. (2006)