The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

AC1L536T     2-[2-[2- (bis(carboxylatomethyl)amino) ethyl...

Synonyms: D04283, 12700-20-8, Multihance (TN), Meglumine gadobenate (JAN), Gadobenate dimeglumine (USAN)
This record was replaced with 105125.
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of 2-[2-[2-(bis(carboxymethyl)amino)ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]-3-phenylmethoxy-propanoic acid

 

High impact information on 2-[2-[2-(bis(carboxymethyl)amino)ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]-3-phenylmethoxy-propanoic acid

  • This study tested whether Gd-BOPTA/Dimeg or Gd-DTPA exerts greater relaxation enhancement for blood and reperfused infarcted myocardium [6].
  • A unique property of Gd-BOPTA/Dimeg is that the contrast effective ion, Gd-BOPTA2-, enters hepatocytes selectively and reversibly through the sinusoidal plasma membrane using transport mechanisms other than the organic anion transport polypeptide [7].
 

Associations of 2-[2-[2-(bis(carboxymethyl)amino)ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]-3-phenylmethoxy-propanoic acid with other chemical compounds

  • Gd-EOB-DTPA and Gd-BOPTA/Dimeg are two paramagnetic contrast agents that are unlikely ECF contrast agents but that are selectively taken up by hepatocytes and yield a selective enhancement of the liver parenchyma on T1-weighted images [8].
 

Analytical, diagnostic and therapeutic context of 2-[2-[2-(bis(carboxymethyl)amino)ethyl-(carboxymethyl)amino]ethyl-(carboxymethyl)amino]-3-phenylmethoxy-propanoic acid

References

  1. Identification of myocardial reperfusion with echo planar magnetic resonance imaging. Discrimination between occlusive and reperfused infarctions. Saeed, M., Wendland, M.F., Yu, K.K., Lauerma, K., Li, H.T., Derugin, N., Cavagna, F.M., Higgins, C.B. Circulation (1994) [Pubmed]
  2. Gd-BOPTA/Dimeg: experimental disease imaging. Cavagna, F., Daprà, M., Maggioni, F., de Haën, C., Felder, E. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. (1991) [Pubmed]
  3. Real-time dynamics of an extravascular magnetic resonance contrast medium in acutely infarcted myocardium using inversion recovery and gradient-recalled echo-planar imaging. Yu, K.K., Saeed, M., Wendland, M.F., Derugin, N., Cavagna, F.M., Higgins, C.B. Investigative radiology. (1992) [Pubmed]
  4. Enhanced tumor detection in the presence of fatty liver disease: cell-specific contrast agents. Kreft, B.P., Tanimoto, A., Baba, Y., Zhao, L., Finn, J.P., Stark, D.D. Journal of magnetic resonance imaging : JMRI. (1994) [Pubmed]
  5. Assessment of myocardial function and perfusion in a canine model of non-occlusive coronary artery stenosis using fast magnetic resonance imaging. Schwitter, J., Saeed, M., Wendland, M.F., Sakuma, H., Bremerich, J., Canet, E., Higgins, C.B. Journal of magnetic resonance imaging : JMRI. (1999) [Pubmed]
  6. Alterations in T1 of normal and reperfused infarcted myocardium after Gd-BOPTA versus GD-DTPA on inversion recovery EPI. Wendland, M.F., Saeed, M., Lauerma, K., Derugin, N., Mintorovitch, J., Cavagna, F.M., Higgins, C.B. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. (1997) [Pubmed]
  7. Gadobenate dimeglumine 0.5 M solution for injection (MultiHance) as contrast agent for magnetic resonance imaging of the liver: mechanistic studies in animals. de Haën, C., La Ferla, R., Maggioni, F. Journal of computer assisted tomography. (1999) [Pubmed]
  8. Liver. III: Gadolinium-based hepatobiliary contrast agents (Gd-EOB-DTPA and Gd-BOPTA/Dimeg). Giovagnoni, A., Paci, E. Magnetic resonance imaging clinics of North America. (1996) [Pubmed]
  9. Evaluation of the hepatocyte-specific contrast agent gadobenate dimeglumine for MR imaging of acute hepatitis in a rat model. Marzola, P., Maggioni, F., Vicinanza, E., Daprà, M., Cavagna, F.M. Journal of magnetic resonance imaging : JMRI. (1997) [Pubmed]
 
WikiGenes - Universities