Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Cebesine 2-(4-amino-3-butoxy- phenyl)carbonyloxyethy...

Synonyms: Lacrimin, Novesina, Novesine, Novesin, Conjuncain, ...

This record was replaced with 4633.

van Rij, G. et al., Harnisch, J.P. et al., Haddad, R., Leys, M. et al.

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Disease relevance of Oxybuprocaine

Following minor surgery performed under topical application of oxybuprocaine (Dorsacaine, Novesin) two patients suffered from fibrinous iritis and moderate corneal swelling [1].
In a group of 68 patients a double-blind study was performed to assess the effect of preoperative oxybuprocaine 0.4% (Dorsacaine, Novesin) eye drops in comparison with a placebo in preventing surgically induced miosis during extracapsular cataract extraction [2].

High impact information on Oxybuprocaine

The influence of oxybuprocaine (Novesine) on the intraocular pressure [3].

Analytical, diagnostic and therapeutic context of Oxybuprocaine

The toxic side-effects of 0.4% Novesine and Chibro-Kerakain were investigated by scanning- and transmission electron microscopy in 15 rabbit corneae each in intervals of 3, 6, 10, 15 and 60 mins [4].

References

Fibrinous iritis due to oxybuprocaine. Haddad, R. The British journal of ophthalmology. (1989) [Pubmed]
Effect of oxybuprocaine 0.4% in preventing surgically induced miosis. van Rij, G., Renardel de Lavalette, J.G., Baarsma, G.S., Jansen, J.T. The British journal of ophthalmology. (1984) [Pubmed]
The influence of oxybuprocaine (Novesine) on the intraocular pressure. Leys, M., van Rij, G., de Heer, L.J. Documenta ophthalmologica. Advances in ophthalmology. (1986) [Pubmed]
Side-effects of local anesthetics on the corneal epithelium of the rabbit eye. Harnisch, J.P., Hoffmann, F., Dumitrescu, L. Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology. (1975) [Pubmed]

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