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Gene Review

AP2S1  -  adaptor-related protein complex 2, sigma 1...

Homo sapiens

Synonyms: AP-2 complex subunit sigma, AP17, Adaptor protein complex AP-2 subunit sigma, Adaptor-related protein complex 2 subunit sigma, CLAPS2, ...
 
 
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Disease relevance of AP2S1

  • The survival of antibiotic-resistant and -sensitive strains of Escherichia coli, Enterococcus faecalis, Enterococcus faecium, Streptococcus equinus, and two environmental isolates, AP17 and AQ62, was examined in estuarine water [1].
 

High impact information on AP2S1

  • Immunoprecipitation reveals that this region determines whether a construct coassemblies with AP50 and AP17, or with AP47 and AP19 [2].
  • A sequence comparison of rat brain AP17 with mouse brain AP19 demonstrates that the small chains are highly related [3].
  • AP17, encoded by human CLAPS2 cDNA, is the small chain of the major clathrin adaptor complex AP-2 associated with mammalian plasma membranes [4].
  • Using specific primers for RT-PCR, mRNAs for AP17Delta and AP17 were found in leukocytes and cultured leukemia cells [4].
  • The finding of a putative intron in a human EST cDNA clone suggests that mRNAs for AP17 and AP17Delta are formed by alternative splicing [4].
 

Biological context of AP2S1

References

 
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