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Gene Review:

NDUFAF3 - NADH dehydrogenase (ubiquinone) complex I,...

Homo sapiens

Synonyms: 2P1, C3orf60, DKFZP564J0123, E3-3, MGC10527

Hammami-Hamza, S. et al., Eichner, J.E. et al., Underwood, J. et al., Haan, M.N. et al.

Haan, Mungas, Gonzalez, Ortiz, Acharya, Jagust,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Psychiatry related information on C3orf60

Those with any E4 and 4-4 combinations had a higher risk for dementia than those with the E3-3 combination [1].

High impact information on C3orf60

A database search revealed that 2P1 was 91% identical to ORF1 of E3-3, a rat gene probably involved in the regulation of alternative splicing [2].
Using RT-PCR, purified spermatids were also shown to express 2P1 [2].
2P1, a novel male mouse cDNA specifically expressed during meiosis [2].
In situ hybridization revealed that 2P1 mRNA was absent in spermatogonia but expressed in spermatocytes [2].
The APO E3-3 homozygote was intermediate on all three [3].

Biological context of C3orf60

Three common phenotypes, APO E 3-2, APO E 3-3, and APO E 4-3, were used in analysis of variance on four quantitative lipid variables [3].

Associations of C3orf60 with chemical compounds

Note that the 2Pi1/2 state is analogous to the 2P1/2 spin-orbit excited state of atomic iodine, which is isoelectronic with TeH [4].

References

Prevalence of dementia in older latinos: the influence of type 2 diabetes mellitus, stroke and genetic factors. Haan, M.N., Mungas, D.M., Gonzalez, H.M., Ortiz, T.A., Acharya, A., Jagust, W.J. Journal of the American Geriatrics Society. (2003) [Pubmed]
2P1, a novel male mouse cDNA specifically expressed during meiosis. Hammami-Hamza, S., Doussau, M., Allemand, I., Segretain, D., Gasc, J.M., Finaz, C. Int. J. Dev. Biol. (2003) [Pubmed]
Phenotypic effects of apolipoprotein structural variation on lipid profiles. IV. Apolipoprotein polymorphisms in a small group of black women from the healthy women study. Eichner, J.E., Kuller, L.H., Ferrell, R.E., Kamboh, M.I. Genet. Epidemiol. (1989) [Pubmed]
Heavy hydrides: H2Te ultraviolet photochemistry. Underwood, J., Chastaing, D., Lee, S., Wittig, C. The Journal of chemical physics. (2005) [Pubmed]

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AgaP_AGAP003819	Anopheles gambiae str. PEST
NDUFAF3	Bos taurus
nuaf-3	Caenorhabditis elegans
NDUFAF3	Canis lupus familiaris
ndufaf3	Danio rerio
CG5569	Drosophila melanogaster
NDUFAF3	Macaca mulatta
Ndufaf3	Mus musculus
NDUFAF3	Pan troglodytes
Ndufaf3	Rattus norvegicus
ndufaf3	Xenopus (Silurana) tropicalis

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