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Gene Review

Caprin1  -  cell cycle associated protein 1

Mus musculus

Synonyms: AL022980, Caprin-1, Cytoplasmic activation-and proliferation-associated protein 1, G5E5, GPI-anchored membrane protein 1, ...
 
 
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High impact information on Caprin1

  • CD59 is a 18- to 20-kDa, GPI-anchored membrane protein that functions as a key regulator of the terminal step of the complement activation cascade [1].
  • We have identified two closely linked (0 cM) conserved DNA sequences (P137/p944B) that flank the translocation breakpoint [2].

References

  1. Identification and functional characterization of a new gene encoding the mouse terminal complement inhibitor CD59. Qian, Y.M., Qin, X., Miwa, T., Sun, X., Halperin, J.A., Song, W.C. J. Immunol. (2000) [Pubmed]
  2. Regional and physical mapping studies characterizing the Greig polysyndactyly 3;7 chromosome translocation, t(3;7)(p21.1;p13). Drabkin, H., Sage, M., Helms, C., Green, P., Gemmill, R., Smith, D., Erickson, P., Hart, I., Ferguson-Smith, A., Ruddle, F. Genomics (1989) [Pubmed]
 
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