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Gene Review:

RIC1 - RAB6A GEF complex partner 1

Homo sapiens

Synonyms: CIP150, Connexin-43-interacting protein of 150 kDa, KIAA1432, Protein RIC1 homolog, RAB6A-GEF complex partner protein 1, ...

Akiyama, M. et al.

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High impact information on KIAA1432

CIP150 associates with Cx43 through its carboxyl terminal domain [1].
When the expression of CIP150 was suppressed using small interfering RNA, the localization to the plasma membrane as well as dye transfer activity of Cx43 was significantly reduced [1].

Biological context of KIAA1432

These results suggest that the newly identified domain is essential for the proper phosphorylation and localization of Cx43, and CIP150 is a novel partner protein targeting this domain [1].

Analytical, diagnostic and therapeutic context of KIAA1432

Molecular cloning and functional analysis of a novel Cx43 partner protein CIP150 [1].

References

Molecular cloning and functional analysis of a novel Cx43 partner protein CIP150. Akiyama, M., Ishida, N., Ogawa, T., Yogo, K., Takeya, T. Biochem. Biophys. Res. Commun. (2005) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP010061	Anopheles gambiae str. PEST
AT3G61480	Arabidopsis thaliana
AT5G28350	Arabidopsis thaliana
RIC1	Bos taurus
R06F6.8	Caenorhabditis elegans
KIAA1432	Canis lupus familiaris
ric1	Danio rerio
Rich	Drosophila melanogaster
KIAA1432	Gallus gallus
LOC717435	Macaca mulatta
MGG_05699	Magnaporthe oryzae 70-15
Ric1	Mus musculus
NCU11228	Neurospora crassa OR74A
RIC1	Pan troglodytes
Ric1	Rattus norvegicus
ric1	Schizosaccharomyces pombe 972h-
ric1	Xenopus (Silurana) tropicalis

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