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Gene Review:

Rpn2 - ribophorin II

Rattus norvegicus

Pirozzi, G. et al., Kreibich, G. et al., Fu, J. et al., Dunn, W.A.

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High impact information on Rpn2

In addition, ribophorin II was identified at the limiting membranes of many nascent autophagic vacuoles [1].
Ribophorin II (63,000 daltons) was only proteolyzed when the luminal face of the microsomal vesicles was made accessible to trypsin by the addition of sublytical detergent concentrations [2].
Localization of ribophorin II to the endoplasmic reticulum involves both its transmembrane and cytoplasmic domains [3].
We report here the complete nucleotide sequence of rat ribophorin II [4].
Rat ribophorin II: molecular cloning and chromosomal localization of a highly conserved transmembrane glycoprotein of the rough endoplasmic reticulum [4].

References

Studies on the mechanisms of autophagy: formation of the autophagic vacuole. Dunn, W.A. J. Cell Biol. (1990) [Pubmed]
Proteins of rough microsomal membranes related to ribosome binding. II. Cross-linking of bound ribosomes to specific membrane proteins exposed at the binding sites. Kreibich, G., Freienstein, C.M., Pereyra, B.N., Ulrich, B.L., Sabatini, D.D. J. Cell Biol. (1978) [Pubmed]
Localization of ribophorin II to the endoplasmic reticulum involves both its transmembrane and cytoplasmic domains. Fu, J., Pirozzi, G., Sanjay, A., Levy, R., Chen, Y., De Lemos-Chiarandini, C., Sabatini, D., Kreibich, G. Eur. J. Cell Biol. (2000) [Pubmed]
Rat ribophorin II: molecular cloning and chromosomal localization of a highly conserved transmembrane glycoprotein of the rough endoplasmic reticulum. Pirozzi, G., Zhou, Z.M., D'Eustachio, P., Sabatini, D.D., Kreibich, G. Biochem. Biophys. Res. Commun. (1991) [Pubmed]

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