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Gene Review:

ZNF236 - zinc finger protein 236

Homo sapiens

Synonyms: ZNF236A, ZNF236B, Zinc finger protein 236

Holmes, D.I. et al., Halama, N. et al.

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High impact information on ZNF236

We sequenced ZNF236 in patients with diabetic nephropathy and diabetes without nephropathy, as well as in unaffected controls [1].
We report the construction of a transcript map of the target region on chromosome 18q22.3-q23 and analysis of the candidate gene ZNF236 [1].
We report the cDNA cloning and characterization of ZNF236, a novel Kruppel-like zinc-finger gene initially identified by its glucose-regulated expression in human mesangial cells using mRNA differential display [2].
Southern zoo blot analysis indicated that ZNF236 is conserved in the genomes of all mammalian species tested, but not in yeast [2].

Associations of ZNF236 with chemical compounds

Cloning and characterization of ZNF236, a glucose-regulated Kruppel-like zinc-finger gene mapping to human chromosome 18q22-q23 [2].

Analytical, diagnostic and therapeutic context of ZNF236

Northern blot analysis showed that ZNF236 is ubiquitously expressed in all human tissues tested [2].

References

The Kruppel-like zinc-finger gene ZNF236 is alternatively spliced and excluded as susceptibility gene for diabetic nephropathy. Halama, N., Yard-Breedijk, A., Vardarli, I., Akkoyun, I., Yard, B., Janssen, B., van der Woude, F.J. Genomics (2003) [Pubmed]
Cloning and characterization of ZNF236, a glucose-regulated Kruppel-like zinc-finger gene mapping to human chromosome 18q22-q23. Holmes, D.I., Wahab, N.A., Mason, R.M. Genomics (1999) [Pubmed]

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