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ARA7  -  Rab5 GTPase-like protein Ara7

Arabidopsis thaliana

Synonyms: ARA-7, ARABIDOPSIS RAB GTPASE HOMOLOG F2B, ATRAB-F2B, ATRAB5B, ATRABF2B, ...
 
 
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High impact information on ARA7

  • Examination of green fluorescent protein (GFP)-tagged proteins indicates that both Ara6 and Ara7 are distributed on a subpopulation of endosomes and suggests their roles in endosomal fusion [1].
  • Colocalization studies of the fusion protein with an endocytic tracer FM4-64 and an endosomal Rab-GTPase Ara7 fused to monomeric red fluorescent protein suggested that BOR1 is transferred from the plasma membrane via the endosomes to the vacuole for degradation [2].
  • In protoplasts, transiently expressed Rha1 and Ara7 colocalized with AtPEP12p and VSR(At-1), two proteins that are known to be present at the prevacuolar compartment (PVC) [3].
  • In this study, we investigated the localization of Rha1 and Ara7, two Arabidopsis proteins that have highly similar amino acid sequence homology to Rab5 in animal cells [3].

References

  1. Ara6, a plant-unique novel type Rab GTPase, functions in the endocytic pathway of Arabidopsis thaliana. Ueda, T., Yamaguchi, M., Uchimiya, H., Nakano, A. EMBO J. (2001) [Pubmed]
  2. Endocytosis and degradation of BOR1, a boron transporter of Arabidopsis thaliana, regulated by boron availability. Takano, J., Miwa, K., Yuan, L., von Wirén, N., Fujiwara, T. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  3. The Arabidopsis rab5 homologs rha1 and ara7 localize to the prevacuolar compartment. Lee, G.J., Sohn, E.J., Lee, M.H., Hwang, I. Plant Cell Physiol. (2004) [Pubmed]
 
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