- The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas. Gini, B., Zanca, C., Guo, D., Matsutani, T., Masui, K., Ikegami, S., Yang, H., Nathanson, D., Villa, G.R., Shackelford, D., Zhu, S., Tanaka, K., Babic, I., Akhavan, D., Lin, K., Assuncao, A., Gu, Y., Bonetti, B., Mortensen, D.S., Xu, S., Raymon, H.K., Cavenee, W.K., Furnari, F.B., James, C.D., Kroemer, G., Heath, J.R., Hege, K., Chopra, R., Cloughesy, T.F., Mischel, P.S. Clin. Cancer Res. (2013)