Structure of the murine Thy-1 gene.
We have cloned the murine Thy-1.1 (AKR) and Thy-1.2 (Balb/c) genes. The complete exon/intron structure and the nucleotide sequence of the Thy-1.2 gene was determined. The gene contains four exons and three intervening sequences. The complete transcriptional unit gives rise to a tissue and developmental stage-specific mRNA of 1850 bp. The 5' end of the gene has multiple initiation sites and a non-TATA box promoter. The 3' end shows a single polyadenylation site after a very long untranslated region.[1]References
- Structure of the murine Thy-1 gene. Giguére, V., Isobe, K., Grosveld, F. EMBO J. (1985) [Pubmed]
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