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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Sultan Darvesh

Department of Medicine

Dalhousie University


Nova Scotia



Name/email consistency: high



  • Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. 2003 - 2012
  • Room 1308, Camp Hill Veterans' Memorial Building 1, 5955 Veterans' Memorial Lane, Halifax, Canada. 2009


  1. Butyrylcholinesterase is associated with β-amyloid plaques in the transgenic APPSWE/PSEN1dE9 mouse model of Alzheimer disease. Darvesh, S., Cash, M.K., Reid, G.A., Martin, E., Mitnitski, A., Geula, C. J. Neuropathol. Exp. Neurol. (2012) [Pubmed]
  2. Biochemical and histochemical comparison of cholinesterases in normal and Alzheimer brain tissues. Darvesh, S., Reid, G.A., Martin, E. Curr. Alzheimer. Res (2010) [Pubmed]
  3. Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants. Darvesh, S., Pottie, I.R., Darvesh, K.V., McDonald, R.S., Walsh, R., Conrad, S., Penwell, A., Mataija, D., Martin, E. Bioorg. Med. Chem. (2010) [Pubmed]
  4. Butyrylcholinesterase activity in multiple sclerosis neuropathology. Darvesh, S., Leblanc, A.M., Macdonald, I.R., Reid, G.A., Bhan, V., Macaulay, R.J., Fisk, J.D. Chem. Biol. Interact. (2010) [Pubmed]
  5. Carbamates with differential mechanism of inhibition toward acetylcholinesterase and butyrylcholinesterase. Darvesh, S., Darvesh, K.V., McDonald, R.S., Mataija, D., Walsh, R., Mothana, S., Lockridge, O., Martin, E. J. Med. Chem. (2008) [Pubmed]
  6. Selective reversible inhibition of human butyrylcholinesterase by aryl amide derivatives of phenothiazine. Darvesh, S., McDonald, R.S., Darvesh, K.V., Mataija, D., Conrad, S., Gomez, G., Walsh, R., Martin, E. Bioorg. Med. Chem. (2007) [Pubmed]
  7. Homocysteine thiolactone and human cholinesterases. Darvesh, S., Walsh, R., Martin, E. Cell. Mol. Neurobiol. (2007) [Pubmed]
  8. On the active site for hydrolysis of aryl amides and choline esters by human cholinesterases. Darvesh, S., McDonald, R.S., Darvesh, K.V., Mataija, D., Mothana, S., Cook, H., Carneiro, K.M., Richard, N., Walsh, R., Martin, E. Bioorg. Med. Chem. (2006) [Pubmed]
  9. Structure-activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives. Darvesh, S., McDonald, R.S., Penwell, A., Conrad, S., Darvesh, K.V., Mataija, D., Gomez, G., Caines, A., Walsh, R., Martin, E. Bioorg. Med. Chem. (2005) [Pubmed]
  10. Differential effects of lipid-lowering agents on human cholinesterases. Darvesh, S., Martin, E., Walsh, R., Rockwood, K. Clin. Biochem. (2004) [Pubmed]
  11. Cholinesterase inhibitors modify the activity of intrinsic cardiac neurons. Darvesh, S., Arora, R.C., Martin, E., Magee, D., Hopkins, D.A., Armour, J.A. Exp. Neurol. (2004) [Pubmed]
  12. Neurobiology of butyrylcholinesterase. Darvesh, S., Hopkins, D.A., Geula, C. Nat. Rev. Neurosci. (2003) [Pubmed]
  13. Enantiomer effects of huperzine A on the aryl acylamidase activity of human cholinesterases. Darvesh, S., Walsh, R., Martin, E. Cell. Mol. Neurobiol. (2003) [Pubmed]
  14. Inhibition of human cholinesterases by drugs used to treat Alzheimer disease. Darvesh, S., Walsh, R., Kumar, R., Caines, A., Roberts, S., Magee, D., Rockwood, K., Martin, E. Alzheimer. Dis. Assoc. Disord (2003) [Pubmed]
  15. Differential distribution of butyrylcholinesterase and acetylcholinesterase in the human thalamus. Darvesh, S., Hopkins, D.A. J. Comp. Neurol. (2003) [Pubmed]
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