Thomayant Prueksaritanont
Department of Pharmacokinetics
Pharmacodynamics and Drug Metabolism
WP75A-203
Merck Sharp and Dohme Corp.
Name/email consistency: high
- Lymphatic transport and catabolism of therapeutic proteins after subcutaneous administration to rats and dogs. Wang, W., Chen, N., Shen, X., Cunningham, P., Fauty, S., Michel, K., Wang, B., Hong, X., Adreani, C., Nunes, C.N., Johnson, C.V., Yin, K.C., Groff, M., Zou, Y., Liu, L., Hamuro, L., Prueksaritanont, T. Drug Metab. Dispos. (2012)
- In vitro and in vivo CYP3A64 induction and inhibition studies in rhesus monkeys: a preclinical approach for CYP3A-mediated drug interaction studies. Prueksaritanont, T., Kuo, Y., Tang, C., Li, C., Qiu, Y., Lu, B., Strong-Basalyga, K., Richards, K., Carr, B., Lin, J.H. Drug Metab. Dispos. (2006)
- Rifampin induces the in vitro oxidative metabolism, but not the in vivo clearance of diclofenac in rhesus monkeys. Prueksaritanont, T., Li, C., Tang, C., Kuo, Y., Strong-Basalyga, K., Carr, B. Drug Metab. Dispos. (2006)
- Complicating factors in safety testing of drug metabolites: kinetic differences between generated and preformed metabolites. Prueksaritanont, T., Lin, J.H., Baillie, T.A. Toxicol. Appl. Pharmacol. (2006)
- Comparative effects of fibrates on drug metabolizing enzymes in human hepatocytes. Prueksaritanont, T., Richards, K.M., Qiu, Y., Strong-Basalyga, K., Miller, A., Li, C., Eisenhandler, R., Carlini, E.J. Pharm. Res. (2005)
- Interconversion pharmacokinetics of simvastatin and its hydroxy acid in dogs: effects of gemfibrozil. Prueksaritanont, T., Qiu, Y., Mu, L., Michel, K., Brunner, J., Richards, K.M., Lin, J.H. Pharm. Res. (2005)
- Disposition of a novel and potent alpha(v)beta3 antagonist in animals, and extrapolation to man. Prueksaritanont, T., Fernandez-Metzler, C., Meng, Y., Barrish, A., Halczenko, W., Rodan, S.B., Hutchinson, J.H., Duggan, M.E., Lin, J.H. Xenobiotica (2004)
- Renal elimination of a novel and potent alphavbeta3 integrin antagonist in animals. Prueksaritanont, T., Hochman, J.H., Meng, Y., Pudvah, N.T., Barrish, A., Ma, B., Yamazaki, M., Fernandez-Metzler, C., Lin, J.H. Xenobiotica (2004)
- The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6. Prueksaritanont, T., Ma, B., Yu, N. Br. J. Clin. Pharmacol (2003)
- Stereoselective hepatic disposition of a diastereomeric pair of alphavbeta3 antagonists in rat. Prueksaritanont, T., Xu, X., Deluna, P., Yamazaki, M., Lin, J.H. Xenobiotica (2003)
- Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization. Prueksaritanont, T., Subramanian, R., Fang, X., Ma, B., Qiu, Y., Lin, J.H., Pearson, P.G., Baillie, T.A. Drug Metab. Dispos. (2002)
- Differences in the absorption, metabolism and biliary excretion of a diastereomeric pair of alphavbeta3-antagonists in rat: limited role of P-glycoprotein. Prueksaritanont, T., Meng, Y., Ma, B., Leppert, P., Hochman, J., Tang, C., Perkins, J., Zrada, M., Meissner, R., Duggan, M.E., Lin, J.H. Xenobiotica (2002)
- Mechanistic studies on metabolic interactions between gemfibrozil and statins. Prueksaritanont, T., Zhao, J.J., Ma, B., Roadcap, B.A., Tang, C., Qiu, Y., Liu, L., Lin, J.H., Pearson, P.G., Baillie, T.A. J. Pharmacol. Exp. Ther. (2002)
- Effects of fibrates on metabolism of statins in human hepatocytes. Prueksaritanont, T., Tang, C., Qiu, Y., Mu, L., Subramanian, R., Lin, J.H. Drug Metab. Dispos. (2002)
- beta-Oxidation of simvastatin in mouse liver preparations. Prueksaritanont, T., Ma, B., Fang, X., Subramanian, R., Yu, J., Lin, J.H. Drug Metab. Dispos. (2001)
