Yoshio Tanaka
Department of Chemical Pharmacology
Toho University School of Pharmaceutical Sciences
2-2-1 Miyama
Funabashi-City
Japan
Name/email consistency: high
- Pharmacological characterization of the beta-adrenoceptor that mediates the relaxant response to noradrenaline in guinea-pig tracheal smooth muscle. Tanaka, Y., Yamashita, Y., Michikawa, H., Horinouchi, T., Koike, K. Naunyn Schmiedebergs Arch. Pharmacol. (2007)
- Adrenaline produces the relaxation of guinea-pig airway smooth muscle primarily through the mediation of beta(2)-adrenoceptors. Tanaka, Y., Yamashita, Y., Horinouchi, T., Koike, K. J. Smooth. Muscle. Res (2005)
- New insights into beta-adrenoceptors in smooth muscle: distribution of receptor subtypes and molecular mechanisms triggering muscle relaxation. Tanaka, Y., Horinouchi, T., Koike, K. Clin. Exp. Pharmacol. Physiol. (2005)
- Beta1-subunit of MaxiK channel in smooth muscle: a key molecule which tunes muscle mechanical activity. Tanaka, Y., Koike, K., Alioua, A., Shigenobu, K., Stefani, E., Toro, L. J. Pharmacol. Sci. (2004)
- Beta1-adrenoceptor-mediated relaxation with isoprenaline and the role of MaxiK channels in guinea-pig esophageal smooth muscle. Tanaka, Y., Shinoda, K., Sekiya, S., Yamaki, F., Shibano, M., Yamashita, Y., Horinouchi, T., Koike, K. J. Smooth. Muscle. Res (2004)
- New insights into the intracellular mechanisms by which PGI2 analogues elicit vascular relaxation: cyclic AMP-independent, Gs-protein mediated-activation of MaxiK channel. Tanaka, Y., Yamaki, F., Koike, K., Toro, L. Curr. Med. Chem. Cardiovasc. Hematol. Agents (2004)
- MaxiK channel roles in blood vessel relaxations induced by endothelium-derived relaxing factors and their molecular mechanisms. Tanaka, Y., Koike, K., Toro, L. J. Smooth. Muscle. Res (2004)
- Pharmacological evidence that tetraethylammonium-sensitive, iberiotoxin-insensitive K+ channels function as a negative feedback element for sympathetic neurotransmission by suppressing omega-conotoxin-GVIA-insensitive Ca2+ channels in the relaxation of rabbit facial vein. Tanaka, Y., Akutsu, A., Tanaka, H., Horinouchi, T., Tsuru, H., Koike, K., Shigenobu, K. Naunyn Schmiedebergs Arch. Pharmacol. (2003)
- Phospholipase C inhibitors suppress spontaneous mechanical activity of guinea pig urinary bladder smooth muscle. Tanaka, Y., Okamoto, T., Imai, T., Horinouchi, T., Tanaka, H., Shigenobu, K., Koike, K. Biol. Pharm. Bull. (2003)
- Evidence for a significant role of a Gs-triggered mechanism unrelated to the activation of adenylyl cyclase in the cyclic AMP-independent relaxant response of guinea-pig tracheal smooth muscle. Tanaka, Y., Yamashita, Y., Yamaki, F., Horinouchi, T., Shigenobu, K., Koike, K. Naunyn Schmiedebergs Arch. Pharmacol. (2003)
- MaxiK channel mediates beta2-adrenoceptor-activated relaxation to isoprenaline through cAMP-dependent and -independent mechanisms in guinea-pig tracheal smooth muscle. Tanaka, Y., Yamashita, Y., Yamaki, F., Horinouchi, T., Shigenobu, K., Koike, K. J. Smooth. Muscle. Res (2003)
- Bk(Ca) channel activity enhances with muscle stretch in guinea-pig urinary bladder smooth muscle. Tanaka, Y., Okamoto, T., Imai, T., Yamamoto, Y., Horinouchi, T., Tanaka, H., Koike, K., Shigenobu, K. Res. Commun. Mol. Pathol. Pharmacol. (2003)
- Evidence for the possible involvement of Ca2+ entry blockade in the relaxation by class I antiarrhythmic drugs in the isolated pig coronary smooth muscle. Tanaka, Y., Kamibayashi, M., Yamashita, Y., Imai, T., Tanaka, H., Nakahara, T., Ishii, K., Shigenobu, K. Naunyn Schmiedebergs Arch. Pharmacol. (2002)
- HNS-32, a novel azulene-1-carboxamidine derivative, inhibits nifedipine-sensitive and -insensitive contraction of the isolated rabbit aorta. Tanaka, Y., Mitani, A., Igarashi, T., Someya, S., Otsuka, K., Imai, T., Yamaki, F., Tanaka, H., Saitoh, M., Nakazawa, T., Noguchi, K., Hashimoto, K., Shigenobu, K. Naunyn Schmiedebergs Arch. Pharmacol. (2001)
- Effects of endothelin-1 on the myogenic contraction of canine cerebral artery in response to quick stretch. Tanaka, Y., Shigenobu, K., Nakayama, K. Res. Commun. Mol. Pathol. Pharmacol. (2001)
- A review of HNS-32: a novel azulene-1-carboxamidine derivative with multiple cardiovascular protective actions. Tanaka, Y., Shigenobu, K. Cardiovasc. Drug. Rev (2001)
- Comparison of the Ca2+ entry channels responsible for mechanical responses of guinea-pig aorta to noradrenaline and thapsigargin using SK&F 96365 and LOE 908. Tanaka, Y., Imai, T., Igarashi, T., Takayanagi, K., Otsuka, K., Yamaki, F., Tanaka, H., Shigenobu, K. Naunyn Schmiedebergs Arch. Pharmacol. (2000)
- NO-mediated MaxiK(Ca) channel activation produces relaxation of guinea pig aorta independently of voltage-dependent L-type Ca(2+) channels. Tanaka, Y., Igarashi, T., Kaneko, H., Yamaki, F., Mochizuki, Y., Aida, M., Taniguchi, H., Tanaka, H., Shigenobu, K. Gen. Pharmacol. (2000)
- Endothelium is involved in the vasorelaxation by an ATP-sensitive K+ channel opener, NIP-121. Tanaka, Y., Yamaki, F., Hirano, H., Otsuka, A., Tanaka, H., Shigenobu, K. Eur. J. Pharmacol. (1999)
- Pharmacologic characteristics of non-prostanoid, non-nitric oxide mediated and endothelium-dependent relaxation of guinea-pig aorta in response to substance P. Tanaka, Y., Kaneko, H., Tanaka, H., Shigenobu, K. Res. Commun. Mol. Pathol. Pharmacol. (1999)
- Glycyrrhetinic acid-sensitive mechanism does not make a major contribution to non-prostanoid, non-nitric oxide mediated endothelium-dependent relaxation of rat mesenteric artery in response to acetylcholine. Tanaka, Y., Otsuka, A., Tanaka, H., Shigenobu, K. Res. Commun. Mol. Pathol. Pharmacol. (1999)
- Role of MaxiK channels in vasoactive intestinal peptide-induced relaxation of rat mesenteric artery. Tanaka, Y., Mochizuki, Y., Hirano, H., Aida, M., Tanaka, H., Toro, L., Shigenobu, K. Eur. J. Pharmacol. (1999)
- Changes in cytosolic Ca2+ measured by use of fura-2 and contraction produced by quick stretch and various stimulants in canine cerebral artery. Tanaka, Y., Nakayama, K., Shigenobu, K. Res. Commun. Mol. Pathol. Pharmacol. (1998)
