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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Dr George G. Holz

Professor of Medicine and Pharmacology

SUNY Upstate Medical University

IHP 4310 at 505 Irving Avenue

Syracuse, NY

United States


Name/email consistency: high



  • Cellular Dynamics Program, Marine Biological Laboratory, Woods Hole, MA, USA. 2008-present.
  • Syracuse University Department of Chemistry, Syracuse, New York, USA. 2010-present.
  • Biocurrents Center, Marine Biological Laboratory, Woods Hole, MA, USA. 200-2008.
  • Department of Physiology and Neuroscience, New York University School of Medicine, New York, USA. 1998 - 2007.
  • Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA. 1990-1998.
  • Tufts University School of Medicine, Department of Physiology, Boston, MA, USA. 1984-1990.
  • University of Illinois College of Medicine, Department of Pharmacology, Chicago, IL, USA. 1978-1984.


  1. Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion. Schwede, F., Chepurny, O.G., Kaufholz, M., Bertinetti, D., Leech, C.A., Cabrera, O., Zhu, Y., Mei, F., Cheng, X., Manning Fox, J.E., MacDonald, P.E., Genieser, H.G., Herberg, F.W., Holz, G.G. Mol. Endocrinol. (2015) [Pubmed]
  2. Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells. Leech, C.A., Dzhura, I., Chepurny, O.G., Kang, G., Schwede, F., Genieser, H.G., Holz, G.G. Prog. Biophys. Mol. Biol. (2011) [Pubmed]
  3. Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1. Leech, C.A., Chepurny, O.G., Holz, G.G. Vitam. Horm. (2010) [Pubmed]
  4. Leptin-stimulated KATP channel trafficking: a new paradigm for β-cell stimulus-secretion coupling?. Holz, G.G., Chepurny, O.G., Leech, C.A. Islets. (2013) [Pubmed]
  5. Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag. Chepurny, O.G., Bertinetti, D., Diskar, M., Leech, C.A., Afshari, P., Tsalkova, T., Cheng, X., Schwede, F., Genieser, H.G., Herberg, F.W., Holz, G.G. Mol. Endocrinol. (2013) [Pubmed]
  6. Epac2A makes a new impact in β-cell biology. Holz, G.G., Chepurny, O.G., Leech, C.A. Diabetes. (2013) [Pubmed]
  7. Regulation of glucose homeostasis by GLP-1. Nadkarni, P., Chepurny, O.G., Holz, G.G. Prog. Mol. Biol. Transl. Sci. (2014) [Pubmed]
  8. New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout mice. Holz, G.G., Leech, C.A., Chepurny, O.G. Biochim. Biophys. Acta. (2014) [Pubmed]
  9. Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors. Holz, G.G., Chepurny, O.G., Schwede, F. Cell. Signal. (2008) [Pubmed]
  10. Cell physiology of cAMP sensor Epac. Holz, G.G., Kang, G., Harbeck, M., Roe, M.W., Chepurny, O.G. J. Physiol. (Lond.) (2006) [Pubmed]
  11. Diabetes outfoxed by GLP-1?. Holz, G.G., Chepurny, O.G. Sci. STKE (2005) [Pubmed]
  12. New insights concerning the glucose-dependent insulin secretagogue action of glucagon-like peptide-1 in pancreatic beta-cells. Holz, G.G., Holz, G. Horm. Metab. Res. (2004) [Pubmed]
  13. Glucagon-like peptide-1 synthetic analogs: new therapeutic agents for use in the treatment of diabetes mellitus. Holz, G.G., Chepurny, O.G. Curr. Med. Chem. (2003) [Pubmed]
  14. Insulinotropic toxins as molecular probes for analysis of glucagon-likepeptide-1 receptor-mediated signal transduction in pancreatic beta-cells. Holz, G.G., Leech, C.A., Habener, J.F. Biochimie (2000) [Pubmed]
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