D.J. Pinto
DuPont Pharmaceuticals Company
Experimental Station
P.O. Box 80500
Wilmington
USA
Name/email consistency: high
- Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa. Pinto, D.J., Orwat, M.J., Wang, S., Fevig, J.M., Quan, M.L., Amparo, E., Cacciola, J., Rossi, K.A., Alexander, R.S., Smallwood, A.M., Luettgen, J.M., Liang, L., Aungst, B.J., Wright, M.R., Knabb, R.M., Wong, P.C., Wexler, R.R., Lam, P.Y. J. Med. Chem. (2001)