Frans H. H. Leenen
Hypertension Unit
University of Ottawa Heart Institute
H3238
40 Ruskin St
Canada
Name/email consistency: high
- Central Sympathetic Inhibition by Mineralocorticoid Receptor But Not Angiotensin II Type 1 Receptor Blockade: Are Prescribed Doses Too Low? Leenen, F.H., Ruzicka, M., Floras, J.S. Hypertension (2012)
- Possible role of brain salt-inducible kinase 1 in responses to central sodium in Dahl rats. Huang, B.S., White, R.A., Leenen, F.H. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2012)
- Central infusion of aliskiren prevents sympathetic hyperactivity and hypertension in Dahl salt-sensitive rats on high salt intake. Huang, B.S., White, R.A., Bi, L., Leenen, F.H. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2012)
- Regulation of hypothalamic renin-angiotensin system and oxidative stress by aldosterone. Huang, B.S., Zheng, H., Tan, J., Patel, K.P., Leenen, F.H. Exp. Physiol. (2011)
- Mechanisms mediating sodium-induced pressor responses in the PVN of Dahl rats. Gabor, A., Leenen, F.H. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2011)
- The central role of the brain aldosterone-"ouabain" pathway in salt-sensitive hypertension. Leenen, F.H. Biochim. Biophys. Acta (2010)
- Pharmacokinetic and antihypertensive profile of amlodipine and felodipine-ER in younger versus older patients with hypertension. Leenen, F.H., Coletta, E. J. Cardiovasc. Pharmacol. (2010)
- Obesity and the prevalence and management of hypertension in Ontario, Canada. Leenen, F.H., McInnis, N.H., Fodor, G. Am. J. Hypertens. (2010)
- Results of the Ontario survey on the prevalence and control of hypertension. Leenen, F.H., Dumais, J., McInnis, N.H., Turton, P., Stratychuk, L., Nemeth, K., Lum-Kwong, M.M., Fodor, G. CMAJ (2008)
- Prevention of renal dysfunction and hypertension by amlodipine after heart transplant. Leenen, F.H., Coletta, E., Davies, R.A. Am. J. Cardiol. (2007)
- Effects of hypertension on cardiovascular responses to epinephrine in humans. Leenen, F.H., Fourney, A., Coletta, E., White, R. Am. J. Physiol. Heart Circ. Physiol. (2007)
- Moving beyond guidelines: are report cards the answer to high rates of uncontrolled hypertension? Ruzicka, M., Leenen, F.H. Curr. Hypertens. Rep. (2006)
- Clinical events in high-risk hypertensive patients randomly assigned to calcium channel blocker versus angiotensin-converting enzyme inhibitor in the antihypertensive and lipid-lowering treatment to prevent heart attack trial. Leenen, F.H., Nwachuku, C.E., Black, H.R., Cushman, W.C., Davis, B.R., Simpson, L.M., Alderman, M.H., Atlas, S.A., Basile, J.N., Cuyjet, A.B., Dart, R., Felicetta, J.V., Grimm, R.H., Haywood, L.J., Jafri, S.Z., Proschan, M.A., Thadani, U., Whelton, P.K., Wright, J.T. Hypertension (2006)
- Aging and cardiac responses to epinephrine in humans: role of neuronal uptake. Leenen, F.H., Coletta, E., Fourney, A., White, R. Am. J. Physiol. Heart Circ. Physiol. (2005)
- Blood pressure lowering, not vascular mechanism of action, is the primary determinant of clinical outcome. Leenen, F.H. Can. J. Cardiol (2004)
- The brain and salt-sensitive hypertension. Leenen, F.H., Ruzicka, M., Huang, B.S. Curr. Hypertens. Rep. (2002)
- Differential effects of once-daily antihypertensive drugs on blood pressure, left ventricular mass and sympathetic activity: Nifedipine-GITS versus felodipine-ER versus enalapril. Leenen, F.H., Myers, M.G., Joyner, C.D., Toal, C.B. Can. J. Cardiol (2002)
- Mortality after coronary artery occlusion in different models of cardiac hypertrophy in rats. Leenen, F.H., Yuan, B. Hypertension (2001)
- Prevention of hypertension by irbesartan in Dahl S rats relates to central angiotensin II type 1 receptor blockade. Leenen, F.H., Yuan, B. Hypertension (2001)
- Central sympathoinhibitory effects of calcium channel blockers. Leenen, F.H., Ruzicka, M., Huang, B.S. Curr. Hypertens. Rep. (2001)
- Isoproterenol-induced cardiac hypertrophy: role of circulatory versus cardiac renin-angiotensin system. Leenen, F.H., White, R., Yuan, B. Am. J. Physiol. Heart Circ. Physiol. (2001)
- Intermittent blood pressure control: potential consequences for outcome. Leenen, F.H. Can. J. Cardiol (1999)
- Brain "ouabain" and angiotensin II contribute to cardiac dysfunction after myocardial infarction. Leenen, F.H., Yuan, B., Huang, B.S. Am. J. Physiol. (1999)









