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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Christopher H. George

Wales Heart Research Institute

Cardiff University School of Medicine

Heath Park

Cardiff CF14 4XN



Name/email consistency: high



  • Wales Heart Research Institute, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK. 2005 - 2008
  • Cardiff University School of Medicine, Department of Cardiology, Wales Heart Research Institute, Heath Park, UK. 2005 - 2007
  • Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff, United Kingdom. 1998 - 2004


  1. Sarcoplasmic reticulum Ca2+ leak in heart failure: mere observation or functional relevance? George, C.H. Cardiovasc. Res. (2008) [Pubmed]
  2. Developing new anti-arrhythmics: clues from the molecular basis of cardiac ryanodine receptor (RyR2) Ca2+-release channel dysfunction. George, C.H., Lai, F.A. Curr. Pharm. Des. (2007) [Pubmed]
  3. Ryanodine receptors and ventricular arrhythmias: emerging trends in mutations, mechanisms and therapies. George, C.H., Jundi, H., Thomas, N.L., Fry, D.L., Lai, F.A. J. Mol. Cell. Cardiol. (2007) [Pubmed]
  4. Alternative splicing of ryanodine receptors modulates cardiomyocyte Ca2+ signaling and susceptibility to apoptosis. George, C.H., Rogers, S.A., Bertrand, B.M., Tunwell, R.E., Thomas, N.L., Steele, D.S., Cox, E.V., Pepper, C., Hazeel, C.J., Claycomb, W.C., Lai, F.A. Circ. Res. (2007) [Pubmed]
  5. Arrhythmogenic mutation-linked defects in ryanodine receptor autoregulation reveal a novel mechanism of Ca2+ release channel dysfunction. George, C.H., Jundi, H., Walters, N., Thomas, N.L., West, R.R., Lai, F.A. Circ. Res. (2006) [Pubmed]
  6. Toward a molecular understanding of the structure-function of ryanodine receptor Ca2+ release channels: perspectives from recombinant expression systems. George, C.H., Yin, C.C., Lai, F.A. Cell Biochem. Biophys. (2005) [Pubmed]
  7. Ryanodine receptor dysfunction in arrhythmia and sudden cardiac death. George, C.H., Thomas, N.L., Lai, F.A. Future. Cardiol (2005) [Pubmed]
  8. Ryanodine receptor regulation by intramolecular interaction between cytoplasmic and transmembrane domains. George, C.H., Jundi, H., Thomas, N.L., Scoote, M., Walters, N., Williams, A.J., Lai, F.A. Mol. Biol. Cell (2004) [Pubmed]
  9. Dysregulated ryanodine receptors mediate cellular toxicity: restoration of normal phenotype by FKBP12.6. George, C.H., Higgs, G.V., Mackrill, J.J., Lai, F.A. J. Biol. Chem. (2003) [Pubmed]
  10. Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes. George, C.H., Higgs, G.V., Lai, F.A. Circ. Res. (2003) [Pubmed]
  11. Intracellular trafficking pathways in the assembly of connexins into gap junctions. George, C.H., Kendall, J.M., Evans, W.H. J. Biol. Chem. (1999) [Pubmed]
  12. Rapid determination of gap junction formation using HeLa cells microinjected with cDNAs encoding wild-type and chimeric connexins. George, C.H., Martin, P.E., Evans, W.H. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
  13. Connexin-aequorin chimerae report cytoplasmic calcium environments along trafficking pathways leading to gap junction biogenesis in living COS-7 cells. George, C.H., Kendall, J.M., Campbell, A.K., Evans, W.H. J. Biol. Chem. (1998) [Pubmed]
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