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J.J. Haddad

Oxygen Signaling Group

Tayside Institute of Child Health

Dundee

Scotland

United Kingdom

[email]@dundee.ac.uk

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Affiliations

Oxygen Signaling Group, Tayside Institute of Child Health, Dundee, Scotland, United Kingdom. 2000 - 2001
Centre for Research into Human Development, Tayside Institute of Child Health, Ninewells Hospital and Medical School, University of Dundee, UK. 2000 - 2001
Tayside Institute of Child Health, Faculty of Medicine, Dentistry & Nursing, Ninewells Hospital and Medical School, UK. 2001

References

Chemioxyexcitation (delta pO2/ROS)-dependent release of IL-1 beta, IL-6 and TNF-alpha: evidence of cytokines as oxygen-sensitive mediators in the alveolar epithelium. Haddad, J.J., Safieh-Garabedian, B., Saadé, N.E., Kanaan, S.A., Land, S.C. Cytokine (2001) [Pubmed]
The ex vivo differential expression of apoptosis signaling cofactors in the developing perinatal lung: essential role of oxygenation during the transition from placental to pulmonary-based respiration. Haddad, J.J., Choudhary, K.K., Land, S.C. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium. Haddad, J.J., Safieh-Garabedian, B., Saadé, N.E., Land, S.C. J. Pharmacol. Exp. Ther. (2001) [Pubmed]
Alpha-melanocyte-related tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor kappaB translocation and activation: evidence for involvement of an interleukin-1beta193-195 receptor antagonism in the alveolar epithelium. Haddad, J.J., Lauterbach, R., Saadé, N.E., Safieh-Garabedian, B., Land, S.C. Biochem. J. (2001) [Pubmed]
The biphasic immunoregulation of pyrimidylpiperazine (Y-40138) is IL-10 sensitive and requires NF-kappa B targeting in the alveolar epithelium. Haddad, J.J., Safieh-Garabedian, B., Saadé, N.E., Land, S.C. Br. J. Pharmacol. (2001) [Pubmed]
Nuclear factor-kappab blockade attenuates but does not abrogate lipopolysaccharide-dependent tumor necrosis factor-alpha biosynthesis in alveolar epithelial cells. Haddad, J.J., Land, S.C. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
A non-hypoxic, ROS-sensitive pathway mediates TNF-alpha-dependent regulation of HIF-1alpha. Haddad, J.J., Land, S.C. FEBS Lett. (2001) [Pubmed]
VX-745. Vertex Pharmaceuticals. Haddad, J.J. Curr. Opin. Investig. Drugs (2001) [Pubmed]
Immunomodulatory potential of thymulin-Zn(2+) in the alveolar epithelium: amelioration of endotoxin-induced cytokine release and partial amplification of a cytoprotective IL-10-sensitive pathway. Haddad, J.J., Land, S.C., Saadé, N.E., Safieh-Garabedian, B. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
Glutathione depletion is associated with augmenting a proinflammatory signal: evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium. Haddad, J.J. Cytokines Cell. Mol. Ther. (2000) [Pubmed]