John R. Cashman
Human BioMolecular Research Institute
5310 Eastgate Mall
San Diego
CA 92121
Name/email consistency: high
- Identification of Human Butyrylcholinesterase Organophosphate-Resistant Variants through a Novel Mammalian Enzyme Functional Screen. Zhang, J., Chen, S., Ralph, E.C., Dwyer, M., Cashman, J.R. J. Pharmacol. Exp. Ther. (2012)
- Substituted heteroaromatic compounds: effect on nicotine self-administration in rats. Cashman, J.R., Okolotowicz, K., Cerny, M., Johnson, R., Janowsky, A., Azar, M.R. Psychopharmacology (Berl.) (2012)
- Inhibition of Bfl-1 with N-aryl maleimides. Cashman, J.R., MacDonald, M., Ghirmai, S., Okolotowicz, K.J., Sergienko, E., Brown, B., Garcia, X., Zhai, D., Dahl, R., Reed, J.C. Bioorg. Med. Chem. Lett. (2010)
- Dual inhibitors of phosphodiesterase-4 and serotonin reuptake. Cashman, J.R., Voelker, T., Zhang, H.T., O'Donnell, J.M. J. Med. Chem. (2009)
- Stereoselective inhibition of serotonin re-uptake and phosphodiesterase by dual inhibitors as potential agents for depression. Cashman, J.R., Voelker, T., Johnson, R., Janowsky, A. Bioorg. Med. Chem. (2009)
- Inhibition of serotonin and norepinephrine reuptake and inhibition of phosphodiesterase by multi-target inhibitors as potential agents for depression. Cashman, J.R., Ghirmai, S. Bioorg. Med. Chem. (2009)
- Immune defects in Alzheimer's disease: new medications development. Cashman, J.R., Ghirmai, S., Abel, K.J., Fiala, M. BMC. Neurosci (2008)
- Role of flavin-containing monooxygenase in drug development. Cashman, J.R. Expert. Opin. Drug. Metab. Toxicol (2008)
- Analysis of flavin-containing monooxygenase 3 genotype data in populations administered the anti-schizophrenia agent olanzapine. Cashman, J.R., Zhang, J., Nelson, M.R., Braun, A. Drug. Metab. Lett (2008)
- Human flavin-containing monooxygenases. Cashman, J.R., Zhang, J. Annu. Rev. Pharmacol. Toxicol. (2006)
- Dynamic medicinal chemistry in the elaboration of morphine-6-glucuronide analogs. Cashman, J.R., MacDougall, J.M. Curr. Top. Med. Chem (2005)
- Some distinctions between flavin-containing and cytochrome P450 monooxygenases. Cashman, J.R. Biochem. Biophys. Res. Commun. (2005)
- Effect of total parenteral nutrition and choline on hepatic flavin-containing and cytochrome P-450 monooxygenase activity in rats. Cashman, J.R., Lattard, V., Lin, J. Drug Metab. Dispos. (2004)
- The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development. Cashman, J.R. Drug Discov. Today (2004)
- Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria. Cashman, J.R., Camp, K., Fakharzadeh, S.S., Fennessey, P.V., Hines, R.N., Mamer, O.A., Mitchell, S.C., Nguyen, G.P., Schlenk, D., Smith, R.L., Tjoa, S.S., Williams, D.E., Yannicelli, S. Curr. Drug Metab. (2003)
- The role of flavin-containing monooxygenases in drug metabolism and development. Cashman, J.R. Curr. Opin. Drug. Discov. Devel (2003)
- Human flavin-containing monooxygenase (form 3): polymorphisms and variations in chemical metabolism. Cashman, J.R. Pharmacogenomics (2002)
- Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation. Cashman, J.R., Zhang, J. Drug Metab. Dispos. (2002)
