Javier Garzón
Instituto Cajal
CSIC, Madrid
Spain
Name/email consistency: high
- Gz mediates the long-lasting desensitization of brain CB1 receptors and is essential for cross-tolerance with morphine. Garzón, J., de la Torre-Madrid, E., Rodríguez-Muñoz, M., Vicente-Sánchez, A., Sánchez-Blázquez, P. Mol. Pain (2009)
- Do pharmacological approaches that prevent opioid tolerance target different elements in the same regulatory machinery? Garzón, J., Rodríguez-Muñoz, M., Sánchez-Blázquez, P. Curr. Drug. Abuse. Rev (2008)
- Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization. Garzón, J., Rodríguez-Muñoz, M., López-Fando, A., Sánchez-Blázquez, P. J. Biol. Chem. (2005)
- The RGSZ2 protein exists in a complex with mu-opioid receptors and regulates the desensitizing capacity of Gz proteins. Garzón, J., Rodríguez-Muñoz, M., López-Fando, A., Sánchez-Blázquez, P. Neuropsychopharmacology (2005)
- Morphine alters the selective association between mu-opioid receptors and specific RGS proteins in mouse periaqueductal gray matter. Garzón, J., Rodríguez-Muñoz, M., Sánchez-Blázquez, P. Neuropharmacology (2005)
- Effector antagonism by the regulators of G protein signalling (RGS) proteins causes desensitization of mu-opioid receptors in the CNS. Garzón, J., Rodríguez-Muñoz, M., de la Torre-Madrid, E., Sánchez-Blázquez, P. Psychopharmacology (Berl.) (2005)
- RGSZ1 and GAIP regulate mu- but not delta-opioid receptors in mouse CNS: role in tachyphylaxis and acute tolerance. Garzón, J., Rodríguez-Muñoz, M., López-Fando, A., García-España, A., Sánchez-Blázquez, P. Neuropsychopharmacology (2004)
- The R7 subfamily of RGS proteins assists tachyphylaxis and acute tolerance at mu-opioid receptors. Garzón, J., López-Fando, A., Sánchez-Blázquez, P. Neuropsychopharmacology (2003)
- Glycosylated phosducin-like protein long regulates opioid receptor function in mouse brain. Garzón, J., Rodríguez-Díaz, M., López-Fando, A., García-España, A., Sánchez-Blázquez, P. Neuropharmacology (2002)
- RGS9 proteins facilitate acute tolerance to mu-opioid effects. Garzón, J., Rodríguez-Díaz, M., López-Fando, A., Sánchez-Blázquez, P. Eur. J. Neurosci. (2001)
- Administration of myr(+)-G(i2)alpha subunits prevents acute tolerance (tachyphylaxis) to mu-opioid effects in mice. Garzón, J., Sánchez-Blázquez, P. Neuropharmacology (2001)
- Transport of CSF antibodies to Galpha subunits across neural membranes requires binding to the target protein and protein kinase C activity. Garzón, J., DeFelipe, J., Rodríguez, J.R., DeAntonio, I., García-España, A., Sánchez-Blázquez, P. Brain Res. Mol. Brain Res. (1999)
- Myr+-Gi2 alpha and Go alpha subunits restore the efficacy of opioids, clonidine and neurotensin giving rise to antinociception in G-protein knock-down mice. Garzón, J., Rodríguez-Díaz, M., DeAntonio, I., DeFelipe, J., Rodríguez, J.R., Sánchez-Blázquez, P. Neuropharmacology (1999)
- Influence of Gz and Gi2 transducer proteins in the affinity of opioid agonists to mu receptors. Garzón, J., Castro, M., Sánchez-Blázquez, P. Eur. J. Neurosci. (1998)
