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John Cuppoletti

Department of Molecular and Cellular Physiology

University of Cincinnati


Ohio 45267-0576



Name/email consistency: high



  • Department of Molecular and Cellular Physiology, University of Cincinnati, Cincinnati, Ohio 45267-0576, USA. 2000 - 2012


  1. Unoprostone isopropyl and metabolite M1 activate BK channels and prevent ET-1-induced [Ca²⁺]i increases in human trabecular meshwork and smooth muscle. Cuppoletti, J., Malinowska, D.H., Tewari, K.P., Chakrabarti, J., Ueno, R. Invest. Ophthalmol. Vis. Sci. (2012) [Pubmed]
  2. Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors. Cuppoletti, J., Blikslager, A.T., Chakrabarti, J., Nighot, P.K., Malinowska, D.H. BMC Pharmacol. (2012) [Pubmed]
  3. Effects of lubiprostone on human uterine smooth muscle cells. Cuppoletti, J., Malinowska, D.H., Chakrabarti, J., Ueno, R. Prostaglandins Other Lipid Mediat. (2008) [Pubmed]
  4. Cellular and molecular effects of unoprostone as a BK channel activator. Cuppoletti, J., Malinowska, D.H., Tewari, K.P., Chakrabarti, J., Ueno, R. Biochim. Biophys. Acta (2007) [Pubmed]
  5. Sites of protein kinase A activation of the human ClC-2 Cl(-) channel. Cuppoletti, J., Tewari, K.P., Sherry, A.M., Ferrante, C.J., Malinowska, D.H. J. Biol. Chem. (2004) [Pubmed]
  6. SPI-0211 activates T84 cell chloride transport and recombinant human ClC-2 chloride currents. Cuppoletti, J., Malinowska, D.H., Tewari, K.P., Li, Q.J., Sherry, A.M., Patchen, M.L., Ueno, R. Am. J. Physiol., Cell Physiol. (2004) [Pubmed]
  7. ClC-2 Cl- channels in human lung epithelia: activation by arachidonic acid, amidation, and acid-activated omeprazole. Cuppoletti, J., Tewari, K.P., Sherry, A.M., Kupert, E.Y., Malinowska, D.H. Am. J. Physiol., Cell Physiol. (2001) [Pubmed]
  8. Activation of human CIC-2 Cl- channels: implications for cystic fibrosis. Cuppoletti, J., Tewari, K.P., Sherry, A.M., Malinowska, D.H. Clin. Exp. Pharmacol. Physiol. (2000) [Pubmed]
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