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Karin U. Schallreuter

1Clinical and Experimental Dermatology

Centre for Skin Sciences

University of Bradford

Bradford BD7 1DP

UK

[email]@bradford.ac.uk

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • 1Clinical and Experimental Dermatology, Centre for Skin Sciences, University of Bradford, Bradford BD7 1DP, UK. 1997 - 2012
  • Institute for Pigmentary Disorders in Association with EM Arndt University Greifswald, Biotechnikum, Greifswald, Germany. 2011
  • Department of Biomedical Sciences, Clinical and Experimental Dermatology, University of Bradford, West Yorkshire, UK. 2002 - 2004
  • Institute for Pigmentary Disorders, Greifswald, Germany. 2002

References

  1. Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 2: epidermal H2O2/ONOO--mediated stress in vitiligo hampers indoleamine 2,3-dioxygenase and aryl hydrocarbon receptor-mediated immune response signaling. Schallreuter, K.U., Salem, M.A., Gibbons, N.C., Maitland, D.J., Marsch, E., Elwary, S.M., Healey, A.R. FASEB J. (2012) [Pubmed]
  2. Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: epidermal H2O2/ONOO--mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low serotonin and melatonin levels. Schallreuter, K.U., Salem, M.A., Gibbons, N.C., Martinez, A., Slominski, R., Lüdemann, J., Rokos, H. FASEB J. (2012) [Pubmed]
  3. The redox--biochemistry of human hair pigmentation. Schallreuter, K.U., Salem, M.M., Hasse, S., Rokos, H. Pigment. Cell. Melanoma. Res (2011) [Pubmed]
  4. Cholesterol regulates melanogenesis in human epidermal melanocytes and melanoma cells. Schallreuter, K.U., Hasse, S., Rokos, H., Chavan, B., Shalbaf, M., Spencer, J.D., Wood, J.M. Exp. Dermatol. (2009) [Pubmed]
  5. Methionine sulfoxide reductases A and B are deactivated by hydrogen peroxide (H2O2) in the epidermis of patients with vitiligo. Schallreuter, K.U., Rübsam, K., Gibbons, N.C., Maitland, D.J., Chavan, B., Zothner, C., Rokos, H., Wood, J.M. J. Invest. Dermatol. (2008) [Pubmed]
  6. Quinones are reduced by 6-tetrahydrobiopterin in human keratinocytes, melanocytes, and melanoma cells. Schallreuter, K.U., Rokos, H., Chavan, B., Gillbro, J.M., Cemeli, E., Zothner, C., Anderson, D., Wood, J.M. Free Radic. Biol. Med. (2008) [Pubmed]
  7. From basic research to the bedside: efficacy of topical treatment with pseudocatalase PC-KUS in 71 children with vitiligo. Schallreuter, K.U., Krüger, C., Würfel, B.A., Panske, A., Wood, J.M. Int. J. Dermatol. (2008) [Pubmed]
  8. Regulation of melanogenesis--controversies and new concepts. Schallreuter, K.U., Kothari, S., Chavan, B., Spencer, J.D. Exp. Dermatol. (2008) [Pubmed]
  9. Basic research confirms coexistence of acquired Blaschkolinear Vitiligo and acrofacial Vitiligo. Schallreuter, K.U., Krüger, C., Rokos, H., Hasse, S., Zothner, C., Panske, A. Arch. Dermatol. Res. (2007) [Pubmed]
  10. Calcium-activated butyrylcholinesterase in human skin protects acetylcholinesterase against suicide inhibition by neurotoxic organophosphates. Schallreuter, K.U., Gibbons, N.C., Elwary, S.M., Parkin, S.M., Wood, J.M. Biochem. Biophys. Res. Commun. (2007) [Pubmed]
  11. Structural and functional alterations in the beta2-adrenoceptor are caused by a point mutation in patients with atopic eczema. Schallreuter, K.U., Wei, Y., Pittelkow, M.R., Swanson, N.N., Gibbons, N.C., Wood, J.M. Exp. Dermatol. (2007) [Pubmed]
  12. Hydrogen peroxide regulates the cholinergic signal in a concentration dependent manner. Schallreuter, K.U., Elwary, S. Life Sci. (2007) [Pubmed]
  13. Advances in melanocyte basic science research. Schallreuter, K.U. Dermatol. Clin (2007) [Pubmed]
  14. Hydrogen peroxide-mediated oxidative stress disrupts calcium binding on calmodulin: more evidence for oxidative stress in vitiligo. Schallreuter, K.U., Gibbons, N.C., Zothner, C., Abou Elloof, M.M., Wood, J.M. Biochem. Biophys. Res. Commun. (2007) [Pubmed]
  15. Functioning methionine sulfoxide reductases A and B are present in human epidermal melanocytes in the cytosol and in the nucleus. Schallreuter, K.U., Rübsam, K., Chavan, B., Zothner, C., Gillbro, J.M., Spencer, J.D., Wood, J.M. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  16. Estrogens can contribute to hydrogen peroxide generation and quinone-mediated DNA damage in peripheral blood lymphocytes from patients with vitiligo. Schallreuter, K.U., Chiuchiarelli, G., Cemeli, E., Elwary, S.M., Gillbro, J.M., Spencer, J.D., Rokos, H., Panske, A., Chavan, B., Wood, J.M., Anderson, D. J. Invest. Dermatol. (2006) [Pubmed]
  17. Functioning methionine-S-sulfoxide reductases A and B are present in human skin. Schallreuter, K.U. J. Invest. Dermatol. (2006) [Pubmed]
  18. Butyrylcholinesterase is present in the human epidermis and is regulated by H2O2: more evidence for oxidative stress in vitiligo. Schallreuter, K.U., Gibbons, N.C., Zothner, C., Elwary, S.M., Rokos, H., Wood, J.M. Biochem. Biophys. Res. Commun. (2006) [Pubmed]
  19. Decreased phenylalanine uptake and turnover in patients with vitiligo. Schallreuter, K.U., Chavan, B., Rokos, H., Hibberts, N., Panske, A., Wood, J.M. Mol. Genet. Metab. (2005) [Pubmed]
  20. Activation/deactivation of acetylcholinesterase by H2O2: more evidence for oxidative stress in vitiligo. Schallreuter, K.U., Elwary, S.M., Gibbons, N.C., Rokos, H., Wood, J.M. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
  21. Human phenylalanine hydroxylase is activated by H2O2: a novel mechanism for increasing the L-tyrosine supply for melanogenesis in melanocytes. Schallreuter, K.U., Wazir, U., Kothari, S., Gibbons, N.C., Moore, J., Wood, J.M. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
  22. In situ and in vitro evidence for DCoH/HNF-1 alpha transcription of tyrosinase in human skin melanocytes. Schallreuter, K.U., Kothari, S., Hasse, S., Kauser, S., Lindsey, N.J., Gibbons, N.C., Hibberts, N., Wood, J.M. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  23. Increased epidermal functioning wild-type p53 expression in vitiligo. Schallreuter, K.U., Behrens-Williams, S., Khaliq, T.P., Picksley, S.M., Peters, E.M., Marles, L.K., Westerhof, W., Miehe, B., Fanghänel, J. Exp. Dermatol. (2003) [Pubmed]
  24. Molecular evidence that halo in Sutton's naevus is not vitiligo. Schallreuter, K.U., Kothari, S., Elwary, S., Rokos, H., Hasse, S., Panske, A. Arch. Dermatol. Res. (2003) [Pubmed]
  25. Decreased photodamage and low incidence of non-melanoma skin cancer in 136 sun-exposed caucasian patients with vitiligo. Schallreuter, K.U., Tobin, D.J., Panske, A. Dermatology. (Basel) (2002) [Pubmed]
  26. Rapid initiation of repigmentation in vitiligo with Dead Sea climatotherapy in combination with pseudocatalase (PC-KUS). Schallreuter, K.U., Moore, J., Behrens-Williams, S., Panske, A., Harari, M. Int. J. Dermatol. (2002) [Pubmed]
  27. Epidermal H(2)O(2) accumulation alters tetrahydrobiopterin (6BH4) recycling in vitiligo: identification of a general mechanism in regulation of all 6BH4-dependent processes?. Schallreuter, K.U., Moore, J., Wood, J.M., Beazley, W.D., Peters, E.M., Marles, L.K., Behrens-Williams, S.C., Dummer, R., Blau, N., Thöny, B. J. Invest. Dermatol. (2001) [Pubmed]
  28. Thioredoxin reductase - its role in epidermal redox status. Schallreuter, K.U., Wood, J.M. J. Photochem. Photobiol. B, Biol. (2001) [Pubmed]
  29. Successful treatment of oxidative stress in vitiligo. Schallreuter, K.U. Skin Pharmacol. Appl. Skin Physiol. (1999) [Pubmed]
  30. The importance of L-phenylalanine transport and its autocrine turnover to L-tyrosine for melanogenesis in human epidermal melanocytes. Schallreuter, K.U., Wood, J.M. Biochem. Biophys. Res. Commun. (1999) [Pubmed]
  31. In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase. Schallreuter, K.U., Moore, J., Wood, J.M., Beazley, W.D., Gaze, D.C., Tobin, D.J., Marshall, H.S., Panske, A., Panzig, E., Hibberts, N.A. J. Investig. Dermatol. Symp. Proc. (1999) [Pubmed]
  32. A review of recent advances on the regulation of pigmentation in the human epidermis. Schallreuter, K.U. Cell. Mol. Biol. (Noisy-le-grand) (1999) [Pubmed]
  33. alpha-MSH can control the essential cofactor 6-tetrahydrobiopterin in melanogenesis. Schallreuter, K.U., Moore, J., Tobin, D.J., Gibbons, N.J., Marshall, H.S., Jenner, T., Beazley, W.D., Wood, J.M. Ann. N. Y. Acad. Sci. (1999) [Pubmed]
  34. 6-Tetrahydrobiopterin functions as a UVB-light switch for de novo melanogenesis. Schallreuter, K.U., Wood, J.M., Körner, C., Harle, K.M., Schulz-Douglas, V., Werner, E.R. Biochim. Biophys. Acta (1998) [Pubmed]
  35. What controls melanogenesis?. Schallreuter, K., Slominski, A., Pawelek, J.M., Jimbow, K., Gilchrest, B.A. Exp. Dermatol. (1998) [Pubmed]
  36. Altered catecholamine synthesis and degradation in the epidermis of patients with atopic eczema. Schallreuter, K.U., Pittelkow, M.R., Swanson, N.N., Beazley, W.D., Körner, C., Ehrke, C., Büttner, G. Arch. Dermatol. Res. (1997) [Pubmed]
 
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