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Long Sen Chang

Institute of Biomedical Sciences

National Sun Yat-Sen University-Kaohsiung Medical University Joint Research Center

National Sun Yat-Sen University

Kaohsiung 804

Taiwan

[email]@*.nsysu.edu.tw

Name/email consistency: high

 
 
 
 
 
 
 

Affiliations

  • Institute of Biomedical Sciences, National Sun Yat-Sen University-Kaohsiung Medical University Joint Research Center, National Sun Yat-Sen University, Kaohsiung 804, Taiwan. 2006 - 2008
  • Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung 804, Taiwan. 1999 - 2006
  • Department of Biochemistry, Kaohsiung Medical College, ROC. 1996 - 1998

References

  1. Genetic organization of Bungarus multicinctus protease inhibitor-like proteins. Chang, L.S., Wang, J.J., Cheng, Y.C., Chou, W.M. Toxicon (2008) [Pubmed]
  2. Purification and characterization of Ophiophagus hannah cytotoxin-like proteins. Chang, L.S., Chen, K.C., Lin, S.R., Huang, H.B. Toxicon (2006) [Pubmed]
  3. Modification of Lys-6 and Lys-65 affects the structural stability of Taiwan cobra phospholipase A2. Chang, L.S., Cheng, Y.C., Chen, C.P. Protein J. (2006) [Pubmed]
  4. Disulfide isomerization and thiol-disulfide exchange of long neurotoxins from the venom of Ophiophagus hannah. Chang, L.S., Lin, S.R., Huang, H.B. Arch. Biochem. Biophys. (2006) [Pubmed]
  5. Purification and characterization of Taiwan cobra venom proteins with weak toxicity. Chang, L.S., Liou, J.C., Lin, S.R., Cheng, Y.C. Toxicon (2005) [Pubmed]
  6. Lys-64 of the A chain is involved in the enzymatic activity and neurotoxic effect of beta-bungarotoxin. Chang, L.S., Chu, Y.P., Cheng, Y.C., Liou, J.C., Yang, C.C. Toxicon (2005) [Pubmed]
  7. Chemical modification of arginine residues of Notechis scutatus scutatus notexin. Chang, L.S., Wu, P.F., Liou, J.C., Chiang-Lin, W.H., Yang, C.C. Toxicon (2004) [Pubmed]
  8. Enrichment of the antibodies against the C-terminus of Taiwan cobra cobrotoxin using dimeric glutaraldehyde-modified toxin as an immunogen. Chang, L.S., Lin, R., Chen, K.C., Chang, C.C. Toxicon (2003) [Pubmed]
  9. Novel neurotoxins from Taiwan banded krait (Bungarus multicinctus) venom: purification, characterization and gene organization. Chang, L.S., Chung, C., Liou, J.C., Chang, C.W., Yang, C.C. Toxicon (2003) [Pubmed]
  10. Functional implication with the metal-binding properties of KChIP1. Chang, L.S., Chen, C.Y., Wu, T.T. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  11. Purification and characterization of a neurotoxin from the venom of Ophiophagus hannah (king cobra). Chang, L.S., Liou, J.C., Lin, S.R., Huang, H.B. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  12. Organization and phylogenetic analysis of kappa-bungarotoxin genes from Bungarus multicinctus (Taiwan banded krait). Chang, L.S., Chung, C., Lin, J., Hong, E. Genetica (2002) [Pubmed]
  13. Differential expression of human 5S snoRNA genes. Chang, L.S., Lin, S.Y., Lieu, A.S., Wu, T.L. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  14. Purification and characterization of a chymotrypsin inhibitor from the venom of Ophiophagus hannah (King Cobra). Chang, L., Chung, C., Huang, H.B., Lin, S. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  15. Refolding of Taiwan cobra neurotoxin: intramolecular cross-link affects its refolding reaction. Chang, L.S., Lin, S.R., Yang, C.C. Arch. Biochem. Biophys. (2001) [Pubmed]
  16. Glutaraldehyde cross-linking alters the environment around Trp(29) of cobrotoxin and the pathway for regaining its fine structure during refolding. Chang, L.S., Lin, S.R., Yang, C.C. J. Pept. Res. (2001) [Pubmed]
  17. Probing the structural diversities of long alpha-neurotoxins by fluorescence quenching studies. Chang, L.S., Lin, S.R., Wang, J.J., Chang, C.C. J. Protein Chem. (2001) [Pubmed]
  18. The multiplicity of cardiotoxins from Naja naja atra (Taiwan cobra) venom. Chang, L.S., Huang, H.B., Lin, S.R. Toxicon (2000) [Pubmed]
  19. Differential contribution of the conserved tyrosine residues to activity and structural stability of Ophiophagus hannah alpha-neurotoxins. Chang, L., Chang, C., Lin, S. J. Pept. Res. (2000) [Pubmed]
  20. Structure-function studies on Taiwan cobra long neurotoxin homolog. Chang, L., Lin, S., Wang, J., Hu, W.P., Wu, B., Huang, H. Biochim. Biophys. Acta (2000) [Pubmed]
  21. Genetic organization of alpha-bungarotoxins from Bungarus multicinctus (Taiwan banded krait): evidence showing that the production of alpha-bungarotoxin isotoxins is not derived from edited mRNAs. Chang, L., Lin, S., Huang, H., Hsiao, M. Nucleic Acids Res. (1999) [Pubmed]
  22. Expression and mutagenesis studies of cobrotoxin from Taiwan cobra. Chang, L.S., Chen, K.C., Wu, B.N., Lin, S.K., Wu, P.F., Hong, Y.R., Yang, C.C. Biochem. Biophys. Res. Commun. (1999) [Pubmed]
  23. Differentially expressed snoRNAs in Bungarus multicinctus (Taiwan banded krait). Chang, L.S., Lin, S.K., Wu, P.F. Biochem. Biophys. Res. Commun. (1998) [Pubmed]
  24. Unfolding/folding studies on cobrotoxin from Taiwan cobra venom: pH and GSH/GSSG govern disulfide isomerization at the C-terminus. Chang, L.S., Lin, S.R., Chang, C.C. Arch. Biochem. Biophys. (1998) [Pubmed]
  25. Disulfide isomerization within the C-terminus of cobrotoxin decelerates by thiol compounds and trinitrophenylation, but accelerates by modification of carboxyl groups. Chang, L., Lin, S., Chang, C., Yang, C. Arch. Biochem. Biophys. (1998) [Pubmed]
  26. Identification of arg-30 as the essential residue for the enzymatic activity of Taiwan cobra phospholipase A2. Chang, L.S., Lin, S.R., Chang, C.C. J. Biochem. (1998) [Pubmed]
  27. cDNA sequence analysis and expression of kappa-bungarotoxin from Taiwan banded krait. Chang, L., Lin, J., Wu, P., Chang, C., Hong, E. Biochem. Biophys. Res. Commun. (1997) [Pubmed]
  28. The structural variations of epsilon-amino groups in phospholipase A2 enzymes from Naja naja atra and Bungarus multicinctus venoms. Chang, L.S., Lin, S.R., Chang, C.C. J. Protein Chem. (1997) [Pubmed]
  29. cDNA sequence analysis of cardiotoxin variants from Taiwan cobra. Chang, L.S., Lin, J., Wu, P.F. Biochem. Mol. Biol. Int. (1997) [Pubmed]
  30. Novel SnoRNAs from Naja naja atra (Taiwan cobra) and Bungarus multicinctus (Taiwan banded krait), form extended sequence complementarity to 5S rRNA. Chang, L., Hong, E. Biochem. Biophys. Res. Commun. (1997) [Pubmed]
  31. Genomic structures of cardiotoxin 4 and cobrotoxin from Naja naja atra (Taiwan cobra). Chang, L.S., Lin, J., Chou, Y.C., Hong, E. Biochem. Biophys. Res. Commun. (1997) [Pubmed]
  32. A novel neurotoxin, cobrotoxin b, from Naja naja atra (Taiwan cobra) venom: purification, characterization, and gene organization. Chang, L.S., Chou, Y.C., Lin, S.R., Wu, B.N., Lin, J., Hong, E., Sun, Y.J., Hsiao, C.D. J. Biochem. (1997) [Pubmed]
  33. cDNA sequence analysis and expression of cardiotoxin V and a new cardiotoxin VII from Naja naja atra (Taiwan cobra). Chang, L.S., Lin, J., Wu, P.F. Biochim. Biophys. Acta (1996) [Pubmed]
 
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