William M. Armstead
Department of Anesthesiology and Critical Care
University of Pennsylvania
Philadelphia
USA
Name/email consistency: high
- Red blood cell-coupled tissue plasminogen activator prevents impairment of cerebral vasodilatory responses through inhibition of c-Jun-N-terminal kinase and potentiation of p38 mitogen-activated protein kinase after cerebral photothrombosis in the newborn pig. Armstead, W.M., Ganguly, K., Riley, J., Kiessling, J.W., Cines, D.B., Higazi, A.A., Zaitsev, S., Muzykantov, V.R. Pediatr. Crit. Care. Med (2011)
- tPA contributes to impairment of ATP and Ca sensitive K channel mediated cerebrovasodilation after hypoxia/ischemia through upregulation of ERK MAPK. Armstead, W.M., Riley, J., Cines, D.B., Higazi, A.A. Brain Res. (2011)
- Glucagon protects against impaired NMDA-mediated cerebrovasodilation and cerebral autoregulation during hypotension after brain injury by activating cAMP protein kinase A and inhibiting upregulation of tPA. Armstead, W.M., Kiessling, J.W., Cines, D.B., Higazi, A.A. J. Neurotrauma (2011)
- Phenylephrine infusion prevents impairment of ATP- and calcium-sensitive potassium channel-mediated cerebrovasodilation after brain injury in female, but aggravates impairment in male, piglets through modulation of ERK MAPK upregulation. Armstead, W.M., Kiessling, J.W., Riley, J., Kofke, W.A., Vavilala, M.S. J. Neurotrauma (2011)
- Nociceptin/orphanin phenylalanine glutamine (FQ) receptor and cardiovascular disease. Armstead, W.M. Cardiovasc. Ther (2011)
- Adrenomedullin prevents sex-dependent impairment of autoregulation during hypotension after piglet brain injury through inhibition of ERK MAPK upregulation. Armstead, W.M., Kiessling, J.W., Bdeir, K., Kofke, W.A., Vavilala, M.S. J. Neurotrauma (2010)
- Signaling, delivery and age as emerging issues in the benefit/risk ratio outcome of tPA For treatment of CNS ischemic disorders. Armstead, W.M., Ganguly, K., Kiessling, J.W., Riley, J., Chen, X.H., Smith, D.H., Stein, S.C., Higazi, A.A., Cines, D.B., Bdeir, K., Zaitsev, S., Muzykantov, V.R. J. Neurochem. (2010)
- PAI-1-derived peptide EEIIMD prevents impairment of cerebrovasodilation by augmenting p38 MAPK upregulation after cerebral hypoxia/ischemia. Armstead, W.M., Riley, J., Kiessling, J.W., Cines, D.B., Higazi, A.A. Am. J. Physiol. Heart Circ. Physiol. (2010)
- SNP improves cerebral hemodynamics during normotension but fails to prevent sex dependent impaired cerebral autoregulation during hypotension after brain injury. Armstead, W.M., Kiessling, J.W., Kofke, W.A., Vavilala, M.S. Brain Res. (2010)
- Impaired cerebral blood flow autoregulation during posttraumatic arterial hypotension after fluid percussion brain injury is prevented by phenylephrine in female but exacerbated in male piglets by extracellular signal-related kinase mitogen-activated protein kinase upregulation. Armstead, W.M., Kiessling, J.W., Kofke, W.A., Vavilala, M.S. Crit. Care Med. (2010)
- Novel plasminogen activator inhibitor-1-derived peptide protects against impairment of cerebrovasodilation after photothrombosis through inhibition of JNK MAPK. Armstead, W.M., Riley, J., Kiessling, J.W., Cines, D.B., Higazi, A.A. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2010)
- uPA modulates the age-dependent effect of brain injury on cerebral hemodynamics through LRP and ERK MAPK. Armstead, W.M., Cines, D.B., Bdeir, K.H., Bdeir, Y., Stein, S.C., Higazi, A.A. J. Cereb. Blood Flow Metab. (2009)
- Red blood cells-coupled tPA prevents impairment of cerebral vasodilatory responses and tissue injury in pediatric cerebral hypoxia/ischemia through inhibition of ERK MAPK activation. Armstead, W.M., Ganguly, K., Kiessling, J.W., Chen, X.H., Smith, D.H., Higazi, A.A., Cines, D.B., Bdeir, K., Zaitsev, S., Muzykantov, V.R. J. Cereb. Blood Flow Metab. (2009)
- uPA impairs cerebrovasodilation after hypoxia/ischemia through LRP and ERK MAPK. Armstead, W.M., Cines, D.B., Bdeir, K., Kulikovskaya, I., Stein, S.C., Higazi, A.A. Brain Res. (2008)
- Urokinase plasminogen activator impairs SNP and PGE2 cerebrovasodilation after brain injury through activation of LRP and ERK MAPK. Armstead, W.M., Christine, A.J., Higazi, A.A., Cines, D.B. J. Neurotrauma (2008)
- Differential activation of ERK, p38, and JNK MAPK by nociceptin/orphanin FQ in the potentiation of prostaglandin cerebrovasoconstriction after brain injury. Armstead, W.M. Eur. J. Pharmacol. (2006)
- Association between intravascular coagulopathy and outcome after traumatic brain injury. Armstead, W.M. Neurol. India (2006)
- Heat shock protein modulation of KATP and KCa channel cerebrovasodilation after brain injury. Armstead, W.M., Hecker, J.G. Am. J. Physiol. Heart Circ. Physiol. (2005)
- Plasminogen activators contribute to age-dependent impairment of NMDA cerebrovasodilation after brain injury. Armstead, W.M., Cines, D.B., Higazie, A.A. Brain Res. Dev. Brain Res. (2005)
- Plasminogen activators contribute to impairment of hypercapnic and hypotensive cerebrovasodilation after cerebral hypoxia/ischemia in the newborn pig. Armstead, W.M., Cines, D.B., Higazi, A.A. Stroke (2005)
- Endothelins and the role of endothelin antagonists in the management of posttraumatic vasospasm. Armstead, W.M. Curr. Pharm. Des. (2004)
- Altered NO function contributes to impairment of uPA and tPA cerebrovasodilation after brain injury. Armstead, W.M., Cines, D.B., Al-Roof Higazi, A. J. Neurotrauma (2004)
- NMDA and age dependent cerebral hemodynamics after traumatic brain injury. Armstead, W.M. Exp. Toxicol. Pathol. (2004)
- Cyclooxygenase-2-dependent superoxide generation contributes to age-dependent impairment of G protein-mediated cerebrovasodilation. Armstead, W.M. Anesthesiology (2003)
- PTK, ERK and p38 MAPK contribute to impaired NMDA-induced vasodilation after brain injury. Armstead, W.M. Eur. J. Pharmacol. (2003)