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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

AGN-PC-004DFJ     2-benzamidopentanedioic acid

Synonyms: SureCN698067, AG-G-42531, ACMC-209mnf, NSC-403570, NSC-635556, ...
 
 
 
 
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High impact information on NSC403570

  • The aim was to measure plasma levels of the prodrug 4-[(2-chloroethyl)(2-mesyloxyethyl) amino] benzoyl-L-glutamic acid (CMDA) and the bifunctional alkylating drug (CJS11) released from it by the action of tumour-localised carboxypeptidase G2 (CPG2) enzyme [1].

References

  1. Antibody-directed enzyme prodrug therapy: pharmacokinetics and plasma levels of prodrug and drug in a phase I clinical trial. Martin, J., Stribbling, S.M., Poon, G.K., Begent, R.H., Napier, M., Sharma, S.K., Springer, C.J. Cancer Chemother. Pharmacol. (1997) [Pubmed]
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