Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AGN-PC-00RJHC 2,3-dihydroxypropyl icosa-5,8,11,14...

Synonyms: AG-D-60312, CTK4B6371, 129691-05-0, 1-Arachidonoyl Glycerol

Fowler, C.J. et al., Vandevoorde, S. et al.

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High impact information on C13857

1-Arachidonoylglycerol inhibited the hydrolysis of [3H]2-oleoylglycerol with a pI50 value of 5.17+/-0.04 (maximum attainable inhibition 88%) [1].
Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro [1].
Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase [2].

References

Cyclooxygenation of the arachidonoyl side chain of 1-arachidonoylglycerol and related compounds block their ability to prevent anandamide and 2-oleoylglycerol metabolism by rat brain in vitro. Fowler, C.J., Tiger, G. Biochem. Pharmacol. (2005) [Pubmed]
Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. Vandevoorde, S., Saha, B., Mahadevan, A., Razdan, R.K., Pertwee, R.G., Martin, B.R., Fowler, C.J. Biochem. Biophys. Res. Commun. (2005) [Pubmed]

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