Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CHEMBL414826 [(2R,3S,5R,6S)-3,4,5- trihydroxy-2,6...

Synonyms: CHEBI:125688, KST-1A5612, KST-1A5613, AC1L4RCX, AC1Q6SGV, ...

Barker, C.J. et al., Barker, C.J. et al.

Barker, Wright, Hughes, Kirk, Michell,

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High impact information on myo-Inositol 1,2,3-trisphosphate

3. Ins(1,2,3)P3 concentration in HL60 cells changed little during stimulation by ATP or fMetLeuPhe or during neutrophilic or monocytic differentiation, and Ins(1,2,3)P3 was unresponsive to vasopressin in WRK1 cells [1].
Remarkably, Ins(1,2,3)P3 turns over fastest during S-phase, when its concentration is lowest [2].

References

Inositol 1,2,3-trisphosphate and inositol 1,2- and/or 2,3-bisphosphate are normal constituents of mammalian cells. Barker, C.J., French, P.J., Moore, A.J., Nilsson, T., Berggren, P.O., Bunce, C.M., Kirk, C.J., Michell, R.H. Biochem. J. (1995) [Pubmed]
Complex changes in cellular inositol phosphate complement accompany transit through the cell cycle. Barker, C.J., Wright, J., Hughes, P.J., Kirk, C.J., Michell, R.H. Biochem. J. (2004) [Pubmed]

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