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Chemical Compound Review: 

Terbium-149     terbium

Synonyms: AC1L42TB, 149Tb, 15065-93-7, Terbium, isotope of mass 149
 
 
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Disease relevance of terbium

  • This study demonstrates high-efficiency sterilisation of single cancer cells in a SCID mouse model of leukaemia using rituximab, a monoclonal antibody that targets CD20, labelled with terbium-149, an alpha-emitting radionuclide [1].

References

  1. Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using 149Tb-rituximab. Beyer, G.J., Miederer, M., Vranjes-Durić, S., Comor, J.J., Künzi, G., Hartley, O., Senekowitsch-Schmidtke, R., Soloviev, D., Buchegger, F. Eur. J. Nucl. Med. Mol. Imaging (2004) [Pubmed]
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