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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

S-20500     8-[4-[[(3R)-5-methoxychroman- 3-yl]-propyl...

Synonyms: AC1L48M1, 143413-70-1
This record was replaced with 202485.
 
 
 
 
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High impact information on 8-[4-[[(3R)-5-methoxychroman-3-yl]-propyl-amino]butyl]-8-azaspiro[4.5]decane-7,9-dione

  • As in behavioral studies, (+)S 20499 was approximately 10-fold more potent than (-)S 20500 in displacing [3H]8-OH-DPAT (IC50 = 2.79 versus 20.3 nM) [1].

References

  1. Anticonflict and discriminative stimulus effects in the pigeon of a new methoxy-chroman 5-HT1A agonist, (+)S 20244 and its enantiomers (+)S 20499 and (-)S 20500. Barrett, J.E., Gamble, E.H., Zhang, L., Guardiola-Lemaitre, B. Psychopharmacology (Berl.) (1994) [Pubmed]
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