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Chemical Compound Review

Tiorphan     2-[(2-benzyl-3-sulfanyl...

Synonyms: THIORPHAN, dl-thiorphan, Prestwick_694, CHEMBL10247, AG-H-06315, ...
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Disease relevance of THIORPHAN

  • However, these doses of Thio significantly reduced %IS/AR when combined with PC with 2-min ischemia to 25.7+/-3.3% and 19.7+/-3.1%, respectively, although this submaximal PC protocol alone did not achieve significant cardioprotection (%IS/AR=35.6+/-4.0%) [1].


  1. Effects of neutral endopeptidase 24.11 inhibition on myocardial infarct size and ischemic preconditioning in rabbits. Nakano, A., Miura, T., Miki, T., Nozawa, Y., Ichikawa, Y., Ura, N., Shimamoto, K. Naunyn Schmiedebergs Arch. Pharmacol. (2002) [Pubmed]
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