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Chemical Compound Review: 

DB03299     3-[[(R)-carboxy-phenyl...

Synonyms: AC1L9M49, N-SUCCINYL PHENYLGLYCINE
 
 
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High impact information on N-SUCCINYL PHENYLGLYCINE

  • The efficiency of the promiscuous NAAAR reaction is enhanced with alternate substrates whose structures mimic that of the SHCHC substrate for the OSBS reaction, for example, the value of k(cat)/K(M) for the enantiomers of N-succinyl phenylglycine, 2.0 x 10(5) M(-1) s(-1), is comparable to that for the OSBS reaction [1].

References

  1. Evolution of enzymatic activity in the enolase superfamily: functional studies of the promiscuous o-succinylbenzoate synthase from Amycolatopsis. Taylor Ringia, E.A., Garrett, J.B., Thoden, J.B., Holden, H.M., Rayment, I., Gerlt, J.A. Biochemistry (2004) [Pubmed]
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