Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

FADROZOLE 4-(1,8- diazabicyclo[4.3.0]nona-6,8- dien-2...

Synonyms: Fadrozol, Fadrozolum, CHEMBL9298, SureCN25491, AGN-PC-00NL4Y, ...

Foidart, A. et al., Mandiki, S.N. et al.

Mandiki, Babiak, Bopopi, Leprieur, Kestemont,

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High impact information on FADROZOLE

Brain aromatase activity (AA) was lower in Fa-treated fish than in other groups [1].

Anatomical context of FADROZOLE

In parallel, OHA and ATD completely blocked the T-induced increase in aromatase mRNA concentration, while VOR and FAD had no effect on these RNA concentrations in the POA-anterior hypothalamus and they decreased them only slightly in the posterior hypothalamus [2].

References

Effects of sex steroids and their inhibitors on endocrine parameters and gender growth differences in Eurasian perch (Perca fluviatilis) juveniles. Mandiki, S.N., Babiak, I., Bopopi, J.M., Leprieur, F., Kestemont, P. Steroids (2005) [Pubmed]
Pre- and post-translational regulation of aromatase by steroidal and non-steroidal aromatase inhibitors. Foidart, A., Tlemçani, O., Harada, N., Abe-Dohmae, S., Balthazart, J. Brain Res. (1995) [Pubmed]

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